Adenine DNA glycosylase Antibodies

AND MUTYH ELISA kits, Adenine DNA glycosylase Proteins

Many biological assays use antibodies to detect Adenine DNA glycosylase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Adenine DNA glycosylase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Adenine DNA glycosylase antibodies...

We validate the specificity of these antibodies to Adenine DNA glycosylase by testing them on tissues known to express MUTYH positively and negatively. Browse below to find the MUTYH antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MUTYH Infographic by Boster Bio

All MUTYH Products

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Product

Figures

Specificity

Applications

Price

Anti-MYH MUTYH Antibody

3 Q&As

Human, Mouse, Rat

$399
Cat # A01618-1
100μl

Anti-MYH (Y176) MUTYH Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A01618Y176
100ul

Anti-MYH MUTYH Antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A01618
100ul

MYH (MUTYH) (NM_001048174) Human Over-expression Lysate

Human

$628
Cat # LS004595
100 µg

Anti-MUTYH Antibody Picoband®

Human, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A01618-2
100 µg/vial

MUTYH Overview

Facts about Adenine DNA glycosylase.

MUTYH 3D structure. Source: alphafold

Adenine DNA glycosylase (MUTYH)

Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to CG by removing the inappropriately paired adenine base from the DNA backbone.

Possesses both adenine and 2- OH-A DNA glycosylase activities. .

Gene Information

Human
Gene Name:	MUTYH
Uniprot:	Q9UIF7
Entrez:	4595

Family

Belongs to:

Nth/MutY family

Alternative Names

CYP2C; EC 3.2.2; EC 3.2.2.-; hMYH; MGC4416; mutY (E. coli) homolog; mutY homolog (E. coli); MutY homolog; MYHA/G-specific adenine DNA glycosylase

Molecular Weight

Mass (kDA):
60.069 kDA

Genomic Context


Human

Location:	1p34.1
Sequence:	1; NC_000001.11 (45329242..45340470, complement)

Subcellular Localizations

Nucleus. Mitochondrion.

Diseases

Malignant Neoplasms
Colorectal Cancer
Polyposis
Adenomatous Polyposis Coli
Colorectal Neoplasms
Adenoma
Neoplasms
Carcinoma
Polyps
Carcinogenesis
Microsatellite Instability
Hereditary Nonpolyposis Colorectal Cancer

Germline Mutation Abnormality
Intestinal Polyposis
Cell Transformation, Neoplastic
Adenomatous Polyps
Malignant Tumor Of Colon
Familial Adenomatous Polyposis, Attenuated (disorder)
Adenocarcinoma

Interacting Proteins

AGTRAP

Pathways

Dna Repair
Mismatch Repair
Base-excision Repair
Pathogenesis
Methylation
Aging
Dna Replication
Cell Death
Cell Cycle
Hypersensitivity
Inflammatory Response
Cell Cycle Checkpoint
Gene Silencing

Programmed Cell Death
Stem Cell Differentiation
Immune Response
Strand Displacement
Cell Division
Translation
Translesion Synthesis

PTMs

Methylation
Oxidation

Phosphorylation
Cleavage

Ubiquitination

Research Areas

Base Excision Repair
Cancer
DNA Repair

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MUTYH

References

PMID: 8682794 by Slupska M.M., et al. Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage.

PMID: 10684930 by Ohtsubo T., et al. Identification of human MutY homolog (hMYH) as a repair enzyme for 2- hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria.