Mucin-4 Antibodies

AND MUC4 ELISA kits, Mucin-4 Proteins

Many biological assays use antibodies to detect Mucin-4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mucin-4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mucin-4 antibodies...

We validate the specificity of these antibodies to Mucin-4 by testing them on tissues known to express MUC4 positively and negatively. Browse below to find the MUC4 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MUC4 Infographic by Boster Bio

All MUC4 Products

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Product

Figures

Specificity

Applications

Price

Anti-MUC4 Antibody Picoband®

4 Q&As

Human, Rat

$370
Cat # PB9147
100 μg/vial

Anti-Mucin 4 MUC4 Antibody

Human, Mouse, Rat

$405
Cat # A01652
100ul

Anti-Mucin-4 MUC4 Antibody

Human, Rat

Flow Cytometry, IHC, WB

$405
Cat # A01652-1
100ul

Anti-MUC4 Antibody Picoband®

Human, Mouse

ELISA, Flow Cytometry, WB

$370
Cat # A01652-2
100 μg/vial

Anti-MUC4 Rabbit Monoclonal Antibody

Human

$370
Cat # M01652-1
100 μl/vial

MUC4 Overview

Facts about Mucin-4.

MUC4 3D structure. Source: alphafold

Mucin-4 (MUC4)

May play a role in tumor progression. Ability to promote tumor growth may be mainly due to repression of apoptosis as opposed to proliferation.

Seems to change cellular behavior through both anti-adhesive effects on cell-cell and cell-extracellular matrix interactions and in its ability to function as an intramembrane ligand for ERBB2. Plays an essential role in cell proliferation and differentiation of epithelial cells by inducing specific phosphorylation of ERBB2.

Gene Information

Human
Gene Name:	MUC4
Uniprot:	Q99102
Entrez:	4585

Family

Belongs to:

No superfamily

Alternative Names

Ascites sialoglycoprotein; ASGP; HSA276359; MUC4; MUC-4; mucin 4, cell surface associated; mucin 4, tracheobronchial; mucin-4; Pancreatic adenocarcinoma mucin; Testis mucin; Tracheobronchial mucin

Molecular Weight

Mass (kDA):
231.518 kDA

Genomic Context


Human

Location:	3q29
Sequence:	3; NC_000003.12 (195746771..195811929, complement)

Tissue Specificity

Expressed in the thymus, thyroid, lung, trachea, esophagus, stomach, small intestine, colon, testis, prostate, ovary, uterus, placenta, and mammary and salivary glands. Expressed in carcinomas arising from some of these epithelia, such as lung cancers, squamous cell carcinomas of the upper aerodigestive tract, mammary carcinomas, biliary tract, colon, and cervix cancers. Minimally or not expressed in the normal pancreas or chronic pancreatitis, but is highly expressed in pancreatic tumors and pancreatic tumor cell lines.

Subcellular Localizations

Membrane; Single-pass membrane protein. Secreted. Isoforms lacking the Cys-rich region, EGF-like domains and transmembrane region are secreted. Secretion occurs by splicing or proteolytic processing.; [Mucin-4 beta chain]: Cell membrane; Single-pass membrane protein.; [Mucin-4 alpha chain]: Secreted.; [Isoform 3]: Cell membrane; Single-pass membrane protein.; [Isoform 11]: Secreted.; [Isoform 15]: Secreted.; [Isoform 17]: Cell membrane; Single-pass membrane protein.