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- Table of Contents
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Mucin-2 Antibodies
AND MUC2 ELISA kits, Mucin-2 Proteins
Many biological assays use antibodies to detect Mucin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mucin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mucin-2 antibodies...
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MUC2 Infographic by Boster Bio
All MUC2 Products
Product
Figures
Specificity
Applications
Price
Anti-MUC2 (Mucin 2) Monoclonal Antibody
1 Citations 3 Q&As
Human
Flow Cytometry, IF, IHC
$486
Cat # M01212
100ug/vial
Cat # M01212
100ug/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01212-1
100 μl
Cat # M01212-1
100 μl
MUC2 Overview
Facts about Mucin-2.
Mucin-2 (MUC2)
Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.
Major constituent of both the outer and inner mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer. .
Gene Information
| Human | |
|---|---|
| Gene Name: | MUC2 |
| Uniprot: | Q02817 |
| Entrez: | 4583 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Intestinal mucin-2; MLP; MUC-2; mucin 2, intestinal/tracheal; mucin 2, oligomeric mucus/gel-forming; mucin-2; mucin-like protein; SMUC
Molecular Weight
Mass (kDA):
540.3 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11p15.5 |
| Sequence: | 11; NC_000011.10 (1074875..1110508) |
Tissue Specificity
Colon, small intestine, colonic tumors, bronchus, cervix and gall bladder.
Subcellular Localizations
Secreted. In the intestine, secreted into the inner and outer mucus layers.
Diseases
- Neoplasms
- Carcinoma
- Malignant Neoplasms
- Adenocarcinoma
- Mucinous Adenocarcinoma
- Stomach Neoplasms
- Metaplasia
- Malignant Neoplasm Of Stomach
- Adenoma
- Malignant Paraganglionic Neoplasm
- Neoplasm Metastasis
- Carcinogenesis
Interacting Proteins
- AGR2
Pathways
- Secretion
- Pathogenesis
- Glycosylation
- Cell Differentiation
- Cell Proliferation
- Localization
- Mucus Secretion
- Methylation
- Transport
- Immune Response
- Cell Growth
- Cell Adhesion
- Dna Methylation
PTMs
- Glycosylation
- Phosphorylation
- Methylation
- Cleavage
- Deglycosylation
- Acetylation
- Sulphation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MUC2
bosterbio.com/bosterbio-gene-info-cards/MUC2
References
PMID: 8300571 by Gum J.R. Jr., et al. Molecular cloning of human intestinal mucin (MUC2) cDNA. Identification of the amino terminus and overall sequence similarity to prepro-von Willebrand factor.
PMID: 1400449 by Gum J.R. Jr., et al. The human MUC2 intestinal mucin has cysteine-rich subdomains located both upstream and downstream of its central repetitive region.
4 Publications of Boster Mucin-2 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.scitotenv.2021.148775, Maternal exposure to sodium ρ-perfluorous nonenoxybenzene sulfonate during preg...
- PubMed ID: 10.1016/j.jff.2020.104045, Bifidobacterium breve ATCC15700 pretreatment prevents alcoholic liver disease th...
- PubMed ID: 10.1016/j.envpol.2019.07.021, Subchronic exposure of environmentally relevant concentrations of F-53B in mice ...
- PubMed ID: , Suppressive and Gut-Reparative Functions of Human Type 1 T Regulatory Cells
*More publications can be found for each product on its corresponding product page