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Mucin-1 Antibodies
AND MUC1 ELISA kits, Mucin-1 Proteins
Many biological assays use antibodies to detect Mucin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mucin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mucin-1 antibodies...
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MUC1 Infographic by Boster Bio
All MUC1 Products
Product
Figures
Specificity
Applications
Price
Human
IHC
$370
Cat # MA1039
100 μg/vial
Cat # MA1039
100 μg/vial
Anti-MUC1 / EMA / CD227 (Epithelial Marker) Monoclonal Antibody
2 Citations 4 Q&As
Human, Mouse
ELISA, Flow Cytometry, IF, IHC
$486
Cat # M00187
100ug/vial
Cat # M00187
100ug/vial
Anti-MUC1 Rabbit Monoclonal Antibody
1 Citations 17 Q&As
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00187-1
100 μl
Cat # M00187-1
100 μl
Anti-MUC1 Antibody Picoband®
4 Citations 16 Q&As
Human, Mouse, Rat
ELISA, IHC, WB
$370
Cat # A00187
100 μg/vial
Cat # A00187
100 μg/vial
Human, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00187-2
100 μg/vial
Cat # A00187-2
100 μg/vial
MUC1 Overview
Facts about Mucin-1.
Mucin-1 (MUC1)
The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein.
May provide a protective layer on epithelial cells from bacterial and enzyme attack. .
Gene Information
| Human | |
|---|---|
| Gene Name: | MUC1 |
| Uniprot: | P15941 |
| Entrez: | 4582 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; CD227 antigen; CD227; DF3 antigen; EMA; Episialin; H23 antigen; H23AG; KL-6; MAM6; MUC-1; MUC1/ZD; mucin 1, cell surface associated; mucin 1, transmembrane; Mucin-1; Peanut-reactive urinary mucin; PEM; PEMMUC-1/SEC; PEMT; Polymorphic epithelial mucin; PUMMUC-1/X; tumor associated epithelial mucin; Tumor-associated epithelial membrane antigen; Tumor-associated mucin
Molecular Weight
Mass (kDA):
122.102 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q22 |
| Sequence: | 1; NC_000001.11 (155185824..155192915, complement) |
Tissue Specificity
Expressed on the apical surface of epithelial cells, especially of airway passages, breast and uterus. Also expressed in activated and unactivated T-cells. Overexpressed in epithelial tumors, such as breast or ovarian cancer and also in non-epithelial tumor cells. Isoform Y is expressed in tumor cells only.
Subcellular Localizations
Apical cell membrane; Single-pass type I membrane protein. Exclusively located in the apical domain of the plasma membrane of highly polarized epithelial cells. After endocytosis, internalized and recycled to the cell membrane. Located to microvilli and to the tips of long filopodial protusions.; [Isoform 5]: Secreted.; [Isoform Y]: Secreted.; [Isoform 9]: Secreted.; [Mucin-1 subunit beta]: Cell membrane. Cytoplasm. Nucleus. On EGF and PDGFRB stimulation, transported to the nucleus through interaction with CTNNB1, a process which is stimulated by phosphorylation. On HRG stimulation, colocalize
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Malignant Neoplasm Of Breast
- Adenocarcinoma
- Mammary Neoplasms
- Neoplasm Metastasis
- Malignant Paraganglionic Neoplasm
- Pancreatic Neoplasm
- Tissue Adhesions
- Cell Invasion
- Pneumonia
- Malignant Neoplasm Of Pancreas
Interacting Proteins
- ABL1
- CEBPB
- EGFR
- MET
- U2AF2
Pathways
- Glycosylation
- Immune Response
- Localization
- Secretion
- Pathogenesis
- Cell Adhesion
- Invasive Growth
- Cell Proliferation
- Cell Growth
- Cell-cell Adhesion
- Hypersensitivity
- Cell Cycle
- Cell Differentiation
PTMs
- Glycosylation
- Phosphorylation
- Cleavage
- Deglycosylation
- Methylation
- Biotinylation
- Oxidation
- Acetylation
Research Areas
- Cancer
- Extracellular Matrix
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MUC1
bosterbio.com/bosterbio-gene-info-cards/MUC1
References
PMID: 2394722 by Lan M.S., et al. Cloning and sequencing of a human pancreatic tumor mucin cDNA.
PMID: 2318825 by Ligtenberg M.J.L., et al. Episialin, a carcinoma-associated mucin, is generated by a polymorphic gene encoding splice variants with alternative amino termini.
23 Publications of Boster Mucin-1 Antibodies & ELISA Kits
- PubMed ID: 10.1111/asj.12206, Establishment and characterization of a dairy goat mammary epithelial cell line ...
- PubMed ID: 10.1016/j.leukres.2021.106565, Long non-coding RNA LINC01003 suppresses the development of multiple myeloma by ...
- PubMed ID: 10.1016/j.envpol.2020.115290, Imidacloprid disturbed the gut barrier function and interfered with bile acids m...
- PubMed ID: 30150280, Combination of fasudil and celecoxib promotes the recovery of injured spinal cor...
- PubMed ID: 29442011, Puerarin protects brain tissue against cerebral ischemia/reperfusion injury by i...
- PubMed ID: 29393449, Effect of cyclooxygenase-2 inhibition on the development of post-traumatic stres...
- PubMed ID: 27895759, Globose, cystic olfactory ensheathing cell tumor: A case report and literature r...
- PubMed ID: 26617722, MicroRNA-101 regulates the viability and invasion of cervical cancer cells
- PubMed ID: 26257474, Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Downregulates the Expr...
- PubMed ID: 28123497, Odontogenic epithelial proliferation is correlated with COX-2 expression in dent...
- PubMed ID: 27562754, Anti-inflammatory Effects of Phyllanthus emblica L on Benzopyrene-Induced Precan...
- PubMed ID: 27297132, miR-144 and targets, c-fos and cyclooxygenase-2 (COX2), modulate synthesis of PG...
- PubMed ID: 26904148, Glycyrrhizic Acid Attenuates Sepsis-Induced Acute Kidney Injury by Inhibiting NF...
- PubMed ID: 26849429, MicroRNA-27b Regulates Mitochondria Biogenesis in Myocytes
- PubMed ID: 25337117, Tolerance of neurite outgrowth to Rho kinase inhibitors decreased by cyclooxygen...
- PubMed ID: 25299052, Toll-Like Receptor 4 Prompts Human Breast Cancer Cells Invasiveness via Lipopoly...
- PubMed ID: 24892779, Preparation and Characterization of a Novel Aspirin Derivative with Anti-Thrombo...
- PubMed ID: 24852102, Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity ...
- PubMed ID: 28637971, Sun, G., Yang, W., Zhang, Y., & Zhao, M. (2017). Esculentoside A ameliorates cec...
- PubMed ID: 24598860, Wang Qs, Yang L, Cui Wy, Chen L, Jiang Yh. Plos One. 2014 Mar 5;9(3):E89149. Doi...
- PubMed ID: 20581853, Wang J, Du Jr, Wang Y, Kuang X, Wang Cy. Acta Pharmacol Sin. 2010 Jul;31(7):791-...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page