Exosome RNA helicase MTR4 Antibodies

AND MTREX ELISA kits, Exosome RNA helicase MTR4 Proteins

Many biological assays use antibodies to detect Exosome RNA helicase MTR4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Exosome RNA helicase MTR4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Exosome RNA helicase MTR4 antibodies...

We validate the specificity of these antibodies to Exosome RNA helicase MTR4 by testing them on tissues known to express MTREX positively and negatively. Browse below to find the MTREX antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MTREX Infographic by Boster Bio

All MTREX Products

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Product

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Specificity

Applications

Price

Anti-SKIV2L2 MTREX Antibody

Human, Mouse

IP, IHC, WB

$405
Cat # A32485
100ul

MTREX (NM_015360) Human Over-expression Lysate

Human

$628
Cat # LS023517
100 µg

MTREX Overview

Facts about Exosome RNA helicase MTR4.

MTREX 3D structure. Source: alphafold

Exosome RNA helicase MTR4 (MTREX)

Part of exosome targeting complexes. Subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short lived RNAs for exosomal degradation.

Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of extended and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei.

Gene Information

Human
Gene Name:	MTREX
Uniprot:	P42285
Entrez:	23517

Family

Belongs to:

helicase family

Alternative Names

Exosome RNA helicase MTR4

Molecular Weight

Mass (kDA):
117.805 kDA

Genomic Context


Human

Location:	5q11.2
Sequence:	5; NC_000005.10 (55307989..55425579)

Subcellular Localizations

Nucleus, nucleoplasm. Nucleus, nucleolus. Nucleus. Nucleus speckle.

Interacting Proteins

MPHOSPH6

PTMs

Acetylation
Isopeptide bond

Phosphoprotein
Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MTREX

References

PMID: 16782053 by Nagahama M., et al. The AAA-ATPase NVL2 is a component of pre-ribosomal particles that interacts with the DExD/H-box RNA helicase DOB1.

PMID: 11719186 by Chen C.-Y., et al. AU binding proteins recruit the exosome to degrade ARE-containing mRNAs.