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MTHFR Antibodies

AND MTHFR ELISA kits, MTHFR Proteins

Many biological assays use antibodies to detect MTHFR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MTHFR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MTHFR antibodies...

We validate the specificity of these antibodies to MTHFR by testing them on tissues known to express MTHFR positively and negatively. Browse below to find the MTHFR antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MTHFR Infographic by Boster Bio

MTHFR protein infographic

All MTHFR Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-MTHFR Antibody

Human, Monkey, Mouse

ELISA, WB

$380
Cat # A00336
100ul

Anti-MTHFR Monoclonal Antibody

Human, Rat

ELISA, IHC, WB

$380
Cat # M00336
100ul

MTHFR (NM_005957) Human Over-expression Lysate

Human

$628
Cat # LS004524
100 µg

MTHFR Overview

Facts about Methylenetetrahydrofolate reductase.

MTHFR 3D structure

MTHFR 3D structure. Source: alphafold

Methylenetetrahydrofolate reductase (MTHFR)

Catalyzes the conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co- substrate for homocysteine remethylation to methionine. .

Gene Information

Human
Gene Name:	MTHFR
Uniprot:	P42898
Entrez:	4524

Gene Information

Family

Belongs to:

methylenetetrahydrofolate reductase family

Family

Alternative Names

EC 1.5.1.20; methylenetetrahydrofolate reductase (NAD(P)H)5,10-methylenetetrahydrofolate reductase (NADPH); methylenetetrahydrofolate reductase

Molecular Weight

Mass (kDA):
74.597 kDA

Molecular Weight

Genomic Context


Human

Location:	1p36.22
Sequence:	1; NC_000001.11 (11785723..11806103, complement)

Diseases

5,10-methylenetetrahydrofolate Reductase Deficiency
Hyperhomocysteinemia
Malignant Neoplasms
Cholangiocarcinoma
Thrombosis
Thrombophilia
Cardiovascular Diseases
Cerebrovascular Accident
Venous Thrombosis
Neoplasms
Vascular Diseases
Hypertensive Disease
Coronary Artery Disease

Thromboembolism
Colorectal Cancer
Diabetes Mellitus
Atherosclerosis
Colorectal Neoplasms
Folic Acid Deficiency
Leukemia

Disease

Pathways

Methylation
Dna Methylation
Pathogenesis
Coagulation
Dna Repair
Dna Hypomethylation
Transport
Aging
Hemostasis
Transsulfuration
Blood Coagulation
Glomerular Filtration
Excretion

Cell Proliferation
Spermatogenesis
Menopause
Platelet Aggregation
Fibrinolysis
Meiosis
Cognition

Pathways

PTMs

Methylation
Reduction
Phosphorylation
Demethylation
Cleavage
Formylation
Acetylation

Oxidation
Deamination
Gpi Anchoring
Cysteinylation
Ubiquitination
Biotinylation
Glycosylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MTHFR

References

PMID: 9680386 by Goyette P., et al. Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR).

PMID: 7920641 by Goyette P., et al. Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification.