MTCL1 Antibodies

AND MTCL1 ELISA kits, MTCL1 Proteins

Many biological assays use antibodies to detect MTCL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MTCL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MTCL1 antibodies...

We validate the specificity of these antibodies to MTCL1 by testing them on tissues known to express MTCL1 positively and negatively. Browse below to find the MTCL1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MTCL1 Infographic by Boster Bio

All MTCL1 Products

Product

Figures

Specificity

Applications

Price

Anti-SOGA2 MTCL1 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A10954
100ul

Anti-MTCL1 Antibody Picoband™

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A10954-1
100 µg/vial

MTCL1 Overview

Facts about Microtubule cross-linking factor 1.

MTCL1 3D structure. Source: alphafold

Microtubule cross-linking factor 1 (MTCL1)

Microtubule-associated factor involved in the late phase of epithelial polarization and microtubule dynamics regulation. Plays a role in the development and maintenance of non-centrosomal microtubule bundles in the lateral membrane in polarized epithelial cells.

Gene Information

Human
Gene Name:	MTCL1
Uniprot:	Q9Y4B5
Entrez:	23255

Family

Belongs to:

SOGA family

Alternative Names

Microtubule cross-linking factor 1

Molecular Weight

Mass (kDA):
209.526 kDA

Genomic Context


Human

Location:	18p11.22
Sequence:	18; NC_000018.10 (8705556..8832778)

Subcellular Localizations

Lateral cell membrane. Apical cell membrane. Cytoplasm, cytoskeleton, spindle pole. Midbody. Cytoplasm, cytoskeleton. Colocalized with microtubules at the base of cilia. Gradually accumulates on the apicobasal microtubule bundles during epithelial cell polarization (By similarity). Colocalized with the apicobasal microtubule bundles running beneath the lateral membrane. Colocalized with microtubule bundles in the spindle pole in mitotic cells and in the midbodies at the end of cytokinesis.

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MTCL1

References

PMID: 23902687 by Sato Y., et al. The novel PAR-1-binding protein MTCL1 has crucial roles in organizing microtubules in polarizing epithelial cells.