Mesothelin Antibodies

AND MSLN ELISA kits, Mesothelin Proteins

Many biological assays use antibodies to detect Mesothelin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mesothelin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mesothelin antibodies...

We validate the specificity of these antibodies to Mesothelin by testing them on tissues known to express MSLN positively and negatively. Browse below to find the MSLN antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MSLN Infographic by Boster Bio

All MSLN Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Mesothelin/MSLN Antibody

16 Q&As

Mouse

IHC

$370
Cat # PB9671
100 μg/vial

Human Mesothelin ELISA Kit PicoKine®

8 Q&As

Human

ELISA

$499
Cat # EK1338
96 wells/kit, with removable strips.

Anti-Mesothelin/MSLN Antibody Picoband®

16 Q&As

Human

ELISA, Flow Cytometry, IHC, IHC-F, ICC, WB

$370
Cat # PB9287
100 μg/vial

Anti-Mesothelin MSLN Monoclonal Antibody

15 Q&As

Human

Flow Cytometry, IHC, WB

$646
Cat # M03266
100ug

Anti-Mesothelin Monoclonal Antibody

15 Q&As

Human

IP, IHC, WB

$370
Cat # M03266-1
100 μl

Mesothelin (MSLN) (NM_005823) Human Over-expression Lysate

Human

$628
Cat # LS010232
100 µg

Anti-Mesothelin/Msln Antibody Picoband®

Mouse

ELISA, WB

$370
Cat # A03266-1
100 µg/vial

MSLN Overview

Facts about Mesothelin.

MSLN 3D structure. Source: alphafold

Mesothelin (MSLN)

Membrane-anchored forms may play a role in cellular adhesion. .

Gene Information

Human
Gene Name:	MSLN
Uniprot:	Q13421
Entrez:	10232

Family

Belongs to:

mesothelin family

Alternative Names

CAK1 antigen; CAK1; megakaryocyte potentiating factor; Mesothelin; MPF; MPFSMRP; MSLN; Pre-pro-megakaryocyte-potentiating factor; SMR; soluble MPF mesothelin related protein

Molecular Weight

Mass (kDA):
68.986 kDA

Genomic Context


Human

Location:	16p13.3
Sequence:	16; NC_000016.10 (760734..768865)

Tissue Specificity

Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).

Subcellular Localizations

Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus.; [Megakaryocyte-potentiating factor]: Secreted.; [Isoform 3]: Secreted.

Diseases

Malignant Neoplasms
Neoplasms
Mesothelioma
Malignant Paraganglionic Neoplasm
Carcinoma
Adenocarcinoma
Malignant Neoplasm Of Pancreas
Pancreatic Neoplasm
Pleural Neoplasms
Malignant Neoplasm Of Ovary
Pleural Mesothelioma
Ovarian Neoplasm
Malignant Pleural Mesothelioma

Neoplasm Metastasis
Neoplasm Invasiveness
Malignant Neoplasm Of Lung
Cell Invasion
Malignant Neoplasm Of Breast
Mammary Neoplasms
Pancreatic Ductal Adenocarcinoma

Pathways

Cell Proliferation
Secretion
Cell Cycle
Cell Adhesion
Methylation
Transport
Melanocyte Differentiation
Immune Response
Cell Division
Phagocytosis

S Phase
Anoikis
Cell Growth
Mating
Viral Replication

PTMs

Cleavage

Methylation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MSLN

References

PMID: 7665620 by Kojima T., et al. Molecular cloning and expression of megakaryocyte potentiating factor cDNA.

PMID: 8552591 by Chang K., et al. Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers.