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- Table of Contents
Facts about RNA-binding protein Musashi homolog 1.
Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' along with other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
Human | |
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Gene Name: | MSI1 |
Uniprot: | O43347 |
Entrez: | 4440 |
Belongs to: |
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Musashi family |
MSI1; Musashi (Drosophila) homolog 1; musashi homolog 1 (Drosophila); Musashi1; Musashi-1; RNA-binding protein Musashi homolog 1
Mass (kDA):
39.125 kDA
Human | |
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Location: | 12q24.31 |
Sequence: | 12; NC_000012.12 (120339662..120369174, complement) |
Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
Cytoplasm. Nucleus.
PMID: 9790759 by Good P., et al. The human Musashi homolog 1 (MSI1) gene encoding the homologue of Musashi/Nrp-1, a neural RNA-binding protein putatively expressed in CNS stem cells and neural progenitor cells.
PMID: 12054577 by Shu H.-J., et al. Expression of the Musashi1 gene encoding the RNA-binding protein in human hepatoma cell lines.