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- Table of Contents
Facts about Max-binding protein MNT.
Binds DNA as a heterodimer with MAX and represses transcription.
Binds to the canonical E box sequence 5'-CACGTG-3' and, with greater affinity, to 5'-CACGCG-3'..
Human | |
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Gene Name: | MNT |
Uniprot: | Q99583 |
Entrez: | 4335 |
Belongs to: |
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No superfamily |
BHLHD3; bHLHd3Max-interacting protein; Class D basic helix-loop-helix protein 3; MAD6; MAX binding protein; MXD6; Myc antagonist MNT; Protein ROX; ROXmax-binding protein MNT
Mass (kDA):
62.3 kDA
Human | |
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Location: | 17p13.3 |
Sequence: | 17; NC_000017.11 (2384073..2401060, complement) |
Nucleus.
PMID: 9184233 by Meroni G., et al. Rox, a novel bHLHZip protein expressed in quiescent cells that heterodimerizes with Max, binds a non-canonical E box and acts as a transcriptional repressor.
PMID: 9598315 by Nigro C.L., et al. The human ROX gene: genomic structure and mutation analysis in human breast tumors.