MNDA Antibodies

AND MNDA ELISA kits, MNDA Proteins

Many biological assays use antibodies to detect MNDA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MNDA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MNDA antibodies...

We validate the specificity of these antibodies to MNDA by testing them on tissues known to express MNDA positively and negatively. Browse below to find the MNDA antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MNDA Infographic by Boster Bio

All MNDA Products

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Product

Figures

Specificity

Applications

Price

Anti-MNDA Antibody

7 Q&As

Human

$360
Cat # A06675
100 µl

Anti-MNDA (V406) Antibody

Human, Mouse, Rat

IHC

$405
Cat # A06675-1
100ul

MNDA (NM_002432) Human Recombinant Protein

$1062
Cat # PROTP41218
20 µg

Anti-MNDA Mouse Monoclonal Antibody [Clone ID: OTI4H6]

Human

IHC, WB

$523
Cat # M06675
100 µl

MNDA (NM_002432) Human Over-expression Lysate

Human

$628
Cat # LS004332
100 µg

MNDA Overview

Facts about Myeloid cell nuclear differentiation antigen.

MNDA 3D structure. Source: alphafold

Myeloid cell nuclear differentiation antigen (MNDA)

May act as a transcriptional activator/repressor from the myeloid lineage. Plays a role in the granulocyte/monocyte cell- specific response to interferon.

Stimulates the DNA binding of the transcriptional repressor protein YY1. .

Gene Information

Human
Gene Name:	MNDA
Uniprot:	P41218
Entrez:	4332

Family

Belongs to:

No superfamily

Alternative Names

myeloid cell nuclear differentiation antigen; PYHIN3

Molecular Weight

Mass (kDA):
45.836 kDA

Genomic Context


Human

Location:	1q23.1
Sequence:	1; NC_000001.11 (158831351..158849502)

Tissue Specificity

Expressed constitutively in cells of the myeloid lineage. Found in promyelocyte stage cells as well as in all other stage cells including peripheral blood monocytes and granulocytes. Also appear in myeloblast cells in some cases of acute myeloid Leukemia.

Subcellular Localizations

Nucleus. Cytoplasm. Uniformly distributed throughout the interphase cell nucleus. Associates with chromatin.

Diseases

Leukemia
Myeloid Leukemia
Neoplasms
Lymphoma
Inflammation
Malignant Neoplasms
Leukemia, Myelocytic, Acute
Lymphoid Leukemia
Lupus Erythematosus, Systemic
Dysmyelopoietic Syndromes
Melanoma
Autoimmune Diseases

Chronic Lymphocytic Leukemia
Autoimmune Reaction
Acute Promyelocytic Leukemia
Cytogenetic Abnormality
Systemic Infection
Myeloid Leukemia, Chronic
Autoimmunity

Interacting Proteins

NSD3

Pathways

Cell Proliferation
Cell Growth
Cell Cycle
Localization
Cell Death
Cell Differentiation
Monocyte Differentiation
Dna Methylation
Methylation
Macrophage Differentiation
Pathogenesis
Cell Activation
Programmed Cell Death

Chemokine Production
Immune Response
Regulation Of Programmed Cell Death
Embryo Development
Inflammatory Response
Reverse Transcription
Chemotaxis

PTMs

Cleavage

Methylation

Citrullination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MNDA

References

PMID: 1644857 by Briggs J.A., et al. Cloning and expression of the human myeloid cell nuclear differentiation antigen: regulation by interferon alpha.

PMID: 1377701 by Burrus G.R., et al. Characterization of the human myeloid cell nuclear differentiation antigen: relationship to interferon-inducible proteins.