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- Table of Contents
Facts about Matrix metalloproteinase-23.
Protease.
May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).. .
Human | |
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Gene Name: | MMP23B |
Uniprot: | O75900 |
Entrez: | 8510 |
Belongs to: |
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peptidase M10A family |
EC 3.4.24.-; Femalysin; matrix metallopeptidase 23B; matrix metalloproteinase 22; matrix metalloproteinase 23B; matrix metalloproteinase in the female reproductive tract; Matrix metalloproteinase-21; Matrix metalloproteinase-22; matrix metalloproteinase-23; MIFR; MIFR-1MMP22femalysin; MMP21; MMP-21; MMP-22; MMP-23; MMP23A
Mass (kDA):
43.935 kDA
Human | |
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Location: | 1p36.33 |
Sequence: | 1; NC_000001.11 (1631681..1635638) |
Predominantly expressed in ovary, testis and prostate.
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Membrane; Single-pass type II membrane protein. A secreted form produced by proteolytic cleavage may also exist.
PMID: 9740677 by Gururajan R., et al. Isolation and characterization of two novel metalloproteinase genes linked to the Cdc2L locus on human chromosome 1p36.3.
PMID: 9988691 by Velasco G., et al. Cloning and characterization of human MMP-23, a new matrix metalloproteinase predominantly expressed in reproductive tissues and lacking conserved domains in other family members.