MKRN3 Antibodies

AND MKRN3 ELISA kits, MKRN3 Proteins

Many biological assays use antibodies to detect MKRN3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MKRN3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MKRN3 antibodies...

We validate the specificity of these antibodies to MKRN3 by testing them on tissues known to express MKRN3 positively and negatively. Browse below to find the MKRN3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MKRN3 Infographic by Boster Bio

All MKRN3 Products

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Anti-MKRN3 Antibody

Human, Mouse, Rat

ELISA, IF, WB

$449
Cat # A05807
0.1 mg

MKRN3 Overview

Facts about Probable E3 ubiquitin-protein ligase makorin-3.

MKRN3 3D structure. Source: alphafold

Probable E3 ubiquitin-protein ligase makorin-3 (MKRN3)

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. .

Gene Information

Human
Gene Name:	MKRN3
Uniprot:	Q13064
Entrez:	7681

Family

Belongs to:

No superfamily

Alternative Names

EC 6.3.2.-; makorin ring finger protein 3; MGC88288; RNF63D15S9; ZFP127RING finger protein 63; Zinc finger protein 127; ZNF127probable E3 ubiquitin-protein ligase makorin-3

Molecular Weight

Mass (kDA):
55.645 kDA

Genomic Context


Human

Location:	15q11.2
Sequence:	15; NC_000015.10 (23565674..23568044)

Tissue Specificity

Ubiquitous.

Diseases

Prader-willi Syndrome
Angelman Syndrome
Obesity
Hyperphagia
Muscle Hypotonia
Uniparental Disomy
Hypogonadism
Tumor Progression
Bone Neoplasms
Narcolepsy
Macrocephaly
Unbalanced Translocation

Smallpox
Osteosarcoma
Malignant Neoplasms
Neoplasms
Nervousness
Pituitary Diseases

Interacting Proteins

BEX2
CRACR2A
ENKD1
ERCC1
FAM110A

FAM124B
FARS2
MDM4
MRPS6
NABP1

POLR1C
PRPF31
PSMA1
RBM41
SCNM1

SF1
SFN
TCEA2
TCHP
TCL1B

TFAP2A
TTC25
UBE2D1

Pathways

Methylation
Dna Methylation
Histone Acetylation
Fertilization
Social Behavior
Oocyte Growth
Synaptic Transmission
Metaphase

Spermatogenesis
Oogenesis

PTMs

Methylation

Research Areas

Zinc Finger

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MKRN3

References

PMID: 10196367 by Jong M.T.C., et al. A novel imprinted gene, encoding a RING zinc-finger protein, and overlapping antisense transcript in the Prader-Willi syndrome critical region.

PMID: 19066619 by Kanber D., et al. A paternal deletion of MKRN3, MAGEL2 and NDN does not result in Prader-Willi syndrome.