MICB Antibodies

AND MICB ELISA kits, MICB Proteins

Many biological assays use antibodies to detect MICB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MICB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MICB antibodies...

We validate the specificity of these antibodies to MICB by testing them on tissues known to express MICB positively and negatively. Browse below to find the MICB antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MICB Infographic by Boster Bio

All MICB Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-MICB Antibody Picoband®

1 Q&As

Human, Mouse

Flow Cytometry, WB

$370
Cat # PB9613
100 μg/vial

Human MICB ELISA Kit PicoKine®

7 Q&As

Human

ELISA

$499
Cat # EK0963
96 wells/kit, with removable strips.

MICB (NM_005931) Human Over-expression Lysate

Human

$628
Cat # LS004277
100 µg

MICB Overview

Facts about MHC class I polypeptide-related sequence B.

MICB 3D structure. Source: alphafold

MHC class I polypeptide-related sequence B (MICB)

Seems to have no function in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells.

Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 contributes to cell lysis.

Gene Information

Human
Gene Name:	MICB
Uniprot:	Q29980
Entrez:	4277

Family

Belongs to:

MHC class I family

Alternative Names

MHC class I chain-related protein B; MHC class I mic-B antigen; MHC class I polypeptide-related sequence B; MICB; MIC-B; PERB11.2MHC class I-like molecule PERB11.2-IMX; stress inducible class I homolog

Molecular Weight

Mass (kDA):
42.646 kDA

Genomic Context


Human

Location:	6p21.33
Sequence:	6; NC_000006.12 (31494881..31511124)

Tissue Specificity

Widely expressed with the exception of the central nervous system where it is absent. Expressed in many, but not all, epithelial tumors of lung, breast, kidney, ovary, prostate and colon. In hepatocellular carcinomas, expressed in tumor cells but not in surrounding non-cancerous tissue.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Binding to human cytomegalovirus glycoprotein UL16 causes sequestration in the endoplasmic reticulum.