MGAT1 Antibodies

AND MGAT1 ELISA kits, MGAT1 Proteins

Many biological assays use antibodies to detect MGAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MGAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MGAT1 antibodies...

We validate the specificity of these antibodies to MGAT1 by testing them on tissues known to express MGAT1 positively and negatively. Browse below to find the MGAT1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MGAT1 Infographic by Boster Bio

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Anti-MGAT1 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A05341
100ul

MGAT1 Overview

Facts about Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase.

MGAT1 3D structure. Source: alphafold

Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (MGAT1)

Initiates complex N-linked carbohydrate formation. Critical for the conversion of high-mannose to hybrid and complex N-glycans.

Gene Information

Human
Gene Name:	MGAT1
Uniprot:	P26572
Entrez:	4245

Family

Belongs to:

glycosyltransferase 13 family

Alternative Names

alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; EC 2.4.1.101; GGNT1; GlcNAc-T I; GlcNac-TI; GLCT1; GLYT1GLCNAC-TI; GNT-1; GNT-I; mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase; MGAT; MGAT1; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I

Molecular Weight

Mass (kDA):
50.878 kDA

Genomic Context


Human

Location:	5q35.3
Sequence:	5; NC_000005.10 (180784780..180815616, complement)

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Nervousness
Autoimmunity
Obesity
Sclerosis
Multiple Sclerosis
Autoimmune Reaction
Anxiety Disorders
Autoimmune Diseases
Diabetes Mellitus
Nerve Degeneration
Pain
Epilepsy
Diabetes Mellitus, Experimental

Growth Arrest
Premature Menopause
Encephalomyelitis
Demyelination
Experimental Autoimmune Encephalomyelitis
Ovarian Failure, Premature
Neoplasm Metastasis

Pathways

Transport
Localization
Endocytosis
Glycosylation
Locomotion
Cell Growth
Fertilization
Oogenesis
Cell Proliferation
Ovulation
Cell Activation
Cell Migration
Brain Development

T Cell Activation
Primary Follicle Stage
Spermatogenesis
Embryo Development
Protein Glycosylation
Flight
Fatty Acid Transport

PTMs

Glycosylation

Acylation

Biotinylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MGAT1

References

PMID: 1702225 by Kumar R., et al. Cloning and expression of N-acetylglucosaminyltransferase I, the medial Golgi transferase that initiates complex N-linked carbohydrate formation.

PMID: 1827260 by Hull E., et al. Organization and localization to chromosome 5 of the human UDP-N- acetylglucosamine:alpha-3-D-mannoside beta-1,2-N- acetylglucosaminyltransferase I gene.