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- Table of Contents
Facts about Homeobox protein MOX-2.
While it activates CDKN1A at a DNA-dependent fashion, it disturbs CDKN2A in a DNA-independent way (PubMed:22206000). May have a regulatory function when quiescent vascular smooth muscle cells reenter the cell cycle.
Human | |
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Gene Name: | MEOX2 |
Uniprot: | P50222 |
Entrez: | 4223 |
Belongs to: |
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No superfamily |
growth arrest-specific homeo box; Growth arrest-specific homeobox; homeobox protein MOX-2; mesenchyme homeo box 2 (growth arrest-specific homeo box); mesenchyme homeobox 2GAX; MOX2mesenchyme homeobox 2 (growth arrest-specific homeo box)
Mass (kDA):
33.594 kDA
Human | |
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Location: | 7p21.2 |
Sequence: | 7; NC_000007.14 (15611212..15686683, complement) |
Embryo and placenta.
Nucleus. Nucleus speckle.
PMID: 7607679 by Grigoriou M., et al. Isolation of the human MOX2 homeobox gene and localization to chromosome 7p22.1-p21.3.
PMID: 7713505 by Lepage D.F., et al. Molecular cloning and localization of the human GAX gene to 7p21.