Myocyte-specific enhancer factor 2C (MEF2C)

Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle- specific enzymes. Controls cardiac morphogenesis and myogenesis, and can also be involved in vascular development.

Plays an important role in hippocampal-dependent memory and learning by suppressing the amount of excitatory synapses and so regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, supply, and electrical activity in the neocortex.