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- Table of Contents
Facts about Microtubule-associated serine/threonine-protein kinase 1.
.
Human | |
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Gene Name: | MAST1 |
Uniprot: | Q9Y2H9 |
Entrez: | 22983 |
Belongs to: |
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protein kinase superfamily |
EC 2.7.11; EC 2.7.11.1; KIAA0973microtubule-associated serine/threonine-protein kinase 1; microtubule associated serine/threonine kinase 1; SAST170; SASTsyntrophin associated serine/threonine kinase; Syntrophin-associated serine/threonine-protein kinase
Mass (kDA):
170.677 kDA
Human | |
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Location: | 19p13.13 |
Sequence: | 19; NC_000019.10 (12838515..12874952) |
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Also localized in the soma of neurons. Observed as punctate clusters in the processes of interneurons and along the cell body periphery. Colocalizes with syntrophins at the cell membrane.
PMID: 30449657 by Tripathy R., et al. Mutations in MAST1 cause mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations.