MAGE-like protein 2 Antibodies

AND Magel2 ELISA kits, MAGE-like protein 2 Proteins

Many biological assays use antibodies to detect MAGE-like protein 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAGE-like protein 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAGE-like protein 2 antibodies...

We validate the specificity of these antibodies to MAGE-like protein 2 by testing them on tissues known to express Magel2 positively and negatively. Browse below to find the Magel2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Magel2 Infographic by Boster Bio

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Anti-MAGEL2 Antibody Picoband®

Human

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A06305-1
100 µg/vial

Magel2 Overview

Facts about MAGE-like protein 2.

MAGE-like protein 2 (Magel2)

Likely enhances ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases, possibly through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) in the E3:substrate complex. Acts as a regulator of retrograde transport via its interaction with VPS35.

Recruited to retromer-containing endosomes and promotes the formation of'Lys- 63'-linked polyubiquitin chains at'Lys-220' of WASHC1 together with TRIM27, leading to encourage endosomal F-actin assembly (By similarity). Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer.

Gene Information

Mouse
Gene Name:	Magel2
Uniprot:	Q9QZ04
Entrez:	27385

Family

Belongs to:

No superfamily

Alternative Names

MAGE-like protein 2

Molecular Weight

Mass (kDA):
137.987 kDA

Genomic Context


Mouse

Location:	7 C\|7 34.37 cM
Sequence:	7;

Tissue Specificity

Expressed predominantly in late development stages and adult brain.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Magel2

References

PMID: 10556298 by Boccaccio I., et al. The human MAGEL2 gene and its mouse homologue are paternally expressed and mapped to the Prader-Willi region.

PMID: 10915770 by Lee S., et al. Expression and imprinting of MAGEL2 suggest a role in Prader-Willi syndrome and the homologous murine imprinting phenotype.