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- Table of Contents
Facts about Melanoma-associated antigen 6.
Proposed to behave through recruitment and/or stabilization of this Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression.
Human | |
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Gene Name: | MAGEA6 |
Uniprot: | P43360 |
Entrez: | 4105 |
Belongs to: |
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No superfamily |
CT1.6MGC52297; MAGE3B antigen; MAGE3B; MAGE-3b; MAGE6member 6; melanoma antigen family A, 6; melanoma-associated antigen 6
Mass (kDA):
34.891 kDA
Human | |
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Location: | Xq28 |
Sequence: | X; NC_000023.11 (152766136..152769729, complement) |
Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes.
PMID: 7927540 by De Plaen E., et al. Structure, chromosomal localization, and expression of 12 genes of the MAGE family.
PMID: 8037761 by Ding M., et al. Cloning and analysis of MAGE-1-related genes.