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- Table of Contents
Facts about Melanoma-associated antigen 2.
Proposed to boost ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and arouses p53/TP53 ubiquitination by TRIM28 possibly in existence of Ubl-conjugating enzyme UBE2H.
Human | |
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Gene Name: | MAGEA2 |
Uniprot: | P43356 |
Entrez: | 4101 |
Belongs to: |
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No superfamily |
Cancer/testis antigen 1.2; CT1.2MGC131923; MAGE-2 antigen; MAGEA2Amember 2; MAGEA2B; melanoma antigen 2; melanoma antigen family A, 2; melanoma-associated antigen 2
Mass (kDA):
35.055 kDA
Human | |
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Location: | Xq28 |
Sequence: | X; NC_000023.11 (152749863..152753942, complement) |
Nucleus. Nucleus, PML body.
PMID: 8276455 by De Smet C., et al. Sequence and expression pattern of the human MAGE2 gene.
PMID: 10854409 by Mallon A.-M., et al. Comparative genome sequence analysis of the Bpa/Str region in mouse and man.