Lef1 Antibodies

AND Lef1 ELISA kits, Lef1 Proteins

Many biological assays use antibodies to detect Lef1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lef1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lef1 antibodies...

We validate the specificity of these antibodies to Lef1 by testing them on tissues known to express Lef1 positively and negatively. Browse below to find the Lef1 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Lef1 Infographic by Boster Bio

All Lef1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-LEF1 Rabbit Monoclonal Antibody

1 Q&As

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M00605
100 μl

Anti-LEF-1 (phospho-S42) Antibody

Human, Rat

$482
Cat # A00605S42
100ul

Anti-Phospho-LEF-1 (S42) Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A00605S42-1
100ul

Anti-LEF1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A00605-2
100 μg/vial

Anti-LEF1 Antibody

Human

$299
Cat # M00605-1
50 µl

Anti-LEF1 Mouse Monoclonal Antibody [Clone ID: OTI10A7]

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M00605-2
100 µl

LEF1 (NM_016269) Human Over-expression Lysate

Human

$628
Cat # LS051176
100 µg

Lef1 Overview

Facts about Lymphoid enhancer-binding factor 1.

Lymphoid enhancer-binding factor 1 (Lef1)

Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis.

TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1 (By similarity). Regulates T-cell receptor alpha enhancer function.

Gene Information

Mouse
Gene Name:	Lef1
Uniprot:	P27782
Entrez:	16842

Family

Belongs to:

TCF/LEF family

Alternative Names

DKFZp586H0919; FLJ46390; LEF1; LEF-1; lymphoid enhancer-binding factor 1; T cell-specific transcription factor 1-alpha; TCF10; TCF1ALPHA; TCF1-alpha; TCF7L3

Molecular Weight

Mass (kDA):
44.059 kDA

Genomic Context


Mouse

Location:	3 G3\|3 60.78 cM
Sequence:	3;

Tissue Specificity

Lymphocytes. Found in distinct epithelial cell compartments of the skin and is abundant in the hair-producing progenitors of the follicle.

Diseases

Malignant Neoplasms
Neoplasms
Cell Transformation, Neoplastic
Carcinoma
Malignant Tumor Of Colon
Leukemia
Tissue Adhesions
Colonic Neoplasms
Malignant Paraganglionic Neoplasm
Skin Neoplasms
Crest Syndrome
Adenomatous Polyposis Coli
Cell Invasion

Melanoma
Polyposis
Colorectal Neoplasms
Lymphoid Leukemia
Neoplasm Metastasis
Chronic Lymphocytic Leukemia
Carcinogenesis

Pathways

Cell Proliferation
Localization
Cell Cycle
Pathogenesis
Cell Differentiation
Regeneration
Cell Growth
Cell Adhesion
Gland Development
Methylation
Cell Development
Mammary Gland Development
Anagen

Cell Death
Osteoblast Differentiation
Cell-cell Adhesion
Neurogenesis
Cell Migration
Cell Division
Angiogenesis

PTMs

Phosphorylation
Methylation
Acetylation
Cleavage
Sumoylation
Demethylation

Dephosphorylation
Reduction
Farnesylation
Hydroxylation
Palmitoylation
Ubiquitination

Research Areas

DNA Repair
DNA replication, Transcription, Translation and Splicing
Signal Transduction
Transcription Factors and Regulators
Wnt Signaling Pathway

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Lef1

References

PMID: 1827423 by Travis A., et al. LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function.

PMID: 8415007 by Fujimoto S., et al. Nucleotide sequence of a cDNA encoding an alternative form of LEF- 1.