LRPAP1 Antibodies

AND LRPAP1 ELISA kits, LRPAP1 Proteins

Many biological assays use antibodies to detect LRPAP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LRPAP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LRPAP1 antibodies...

We validate the specificity of these antibodies to LRPAP1 by testing them on tissues known to express LRPAP1 positively and negatively. Browse below to find the LRPAP1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LRPAP1 Infographic by Boster Bio

All LRPAP1 Products

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Product

Figures

Specificity

Applications

Price

Anti-LRPAP1 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A04521
100ul

LRPAP1 (NM_002337) Human Recombinant Protein

$813
Cat # PROTP30533
20 µg

Mouse LRPAP Recombinant Protein

SDS-PAGE

$250
Cat # PROTP55302
Starting from 20ug

Anti-LRPAP1 Antibody (C-term)

Human

Flow Cytometry, IHC-P, WB

$299
Cat # A04521-1
80 µl

LRPAP1 (NM_002337) Human Over-expression Lysate

Human

$628
Cat # LS004043
100 µg

LRPAP1 Overview

Facts about Alpha-2-macroglobulin receptor-associated protein.

LRPAP1 3D structure. Source: alphafold

Alpha-2-macroglobulin receptor-associated protein (LRPAP1)

Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway. .

Gene Information

Human
Gene Name:	LRPAP1
Uniprot:	P30533
Entrez:	4043

Family

Belongs to:

alpha-2-MRAP family

Alternative Names

A2MRAP; A2MRAPMRAP; A2RAP; alpha-2-macroglobulin receptor-associated protein 1; alpha-2-macroglobulin receptor-associated protein; alpha-2-MRAP; HBP44; lipoprotein receptor associated protein; low density lipoprotein receptor-related protein associated protein 1; Low density lipoprotein receptor-related protein-associated protein 1; low density lipoprotein-related protein-associated protein 1(alpha-2-macroglobulin receptor-associated protein 1); LRPAP; LRPAP1; MGC138272; RAP

Molecular Weight

Mass (kDA):
41.466 kDA

Genomic Context


Human

Location:	4p16.3
Sequence:	4; NC_000004.12 (3503597..3532497, complement)

Subcellular Localizations

Rough endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment lumen. Golgi apparatus, cis-Golgi network. Golgi apparatus lumen. Endosome lumen. Cell surface. May be associated with receptors at the cell surface.

Diseases

Alzheimer's Disease
Cholecystolithiasis
Malignant Neoplasms
Neurodegenerative Disorders
Dementia
Coronary Artery Disease
Malignant Neoplasm Of Gallbladder
Atherosclerosis
Wolf-hirschhorn Syndrome
Coronary Heart Disease
Gallbladder Neoplasm
Biliary Tract Cancer
Infarction

Cholelithiasis
Bile Duct Carcinoma
Thromboembolism
Malignant Neoplasm Of Urinary Bladder
Carcinoma
Venous Thrombosis
Dementia, Vascular

Interacting Proteins

LDLR
LRP1
SORT1
VLDLR

Pathways

Endocytosis
Localization
Receptor-mediated Endocytosis
Transport
Cell Development
Gallstone Formation
Regulation Of Gene Expression
Metaphase

Cognition
Ovulation
Cholesterol Homeostasis

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LRPAP1

References

PMID: 1712782 by Strickland D.K., et al. Primary structure of alpha 2-macroglobulin receptor-associated protein. Human homologue of a Heymann nephritis antigen.

PMID: 9782079 by Van Leuven F., et al. Analysis of the human LRPAP1 gene coding for the lipoprotein receptor-associated protein: identification of 22 polymorphisms and one mutation.