LRP12 Antibodies

AND LRP12 ELISA kits, LRP12 Proteins

Many biological assays use antibodies to detect LRP12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LRP12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LRP12 antibodies...

We validate the specificity of these antibodies to LRP12 by testing them on tissues known to express LRP12 positively and negatively. Browse below to find the LRP12 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LRP12 Infographic by Boster Bio

All LRP12 Products

Product

Figures

Specificity

Applications

Price

Anti-LRP12 Antibody

Human

ELISA, WB

$380
Cat # A10924
100ul

LRP12 (NM_013437) Human Over-expression Lysate

Human

$628
Cat # LS029967
100 µg

LRP12 Overview

Facts about Low-density lipoprotein receptor-related protein 12.

LRP12 3D structure. Source: alphafold

Low-density lipoprotein receptor-related protein 12 (LRP12)

Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.

Gene Information

Human
Gene Name:	LRP12
Uniprot:	Q9Y561
Entrez:	29967

Family

Belongs to:

LDLR family

Alternative Names

DKFZp762O2113; FAM4A1; LRP12; Protein FAM4A1; Protein HELG; RAY1; SEN4; ST7; subfamily A, member 1; suppression of tumorigenicity 7 (breast); suppression of tumorigenicity 7; suppressor of tumorigenicity 7 protein; TSG7

Molecular Weight

Mass (kDA):
94.984 kDA

Genomic Context


Human

Location:	8q22.3
Sequence:	8; NC_000008.11 (104489231..104589024, complement)

Tissue Specificity

Widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas, but not in tissues consisting of a large number of epithelial cells, such as liver and kidney. Expressed at very low levels in a number of tumor-derived cell lines.

Subcellular Localizations

Membrane; Single-pass type I membrane protein. Membrane, coated pit.

Diseases

Neoplasms
Precancerous Conditions
Mouth Neoplasms
Malignant Neoplasm Of Mouth
Malignant Squamous Cell Neoplasm
Malignant Neoplasms
Congenital Neurologic Anomalies
Schizophrenia

Shwachman Syndrome
Carcinoma

Interacting Proteins

NMRK2
RACK1
ZFYVE9

Pathways

Endocytosis
Neuroblast Migration

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LRP12

References

PMID: 9927190 by Qing J., et al. Cloning and characterization of a novel gene encoding a putative transmembrane protein with altered expression in some human transformed and tumor-derived cell lines.

PMID: 12809483 by Battle M.A., et al. ST7 is a novel low-density lipoprotein receptor-related protein (LRP) with a cytoplasmic tail that interacts with proteins related to signal transduction pathways.