Lrig1 Antibodies

AND Lrig1 ELISA kits, Lrig1 Proteins

Many biological assays use antibodies to detect Lrig1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lrig1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lrig1 antibodies...

We validate the specificity of these antibodies to Lrig1 by testing them on tissues known to express Lrig1 positively and negatively. Browse below to find the Lrig1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Lrig1 Infographic by Boster Bio

All Lrig1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-LRIG1 Antibody Picoband®

13 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # A04613-1
100 μg/vial

LRIG1 (NM_015541) Human Recombinant Protein

$813
Cat # PROTQ96JA1
20 µg

LRIG1 (NM_015541) Human Over-expression Lysate

Human

$960
Cat # LS026018
100 µg

Human LRIG1 ELISA Kit PicoKine®

Human

ELISA

$750
Cat # EK2237
96 wells/kit, with removable strips.

Anti-LRIG1 Antibody Picoband®

Human

ELISA, WB

$370
Cat # A04613-2
100 µg/vial

Lrig1 Overview

Facts about Leucine-rich repeats and immunoglobulin-like domains protein 1.

Leucine-rich repeats and immunoglobulin-like domains protein 1 (Lrig1)

Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism which involves enhancement of receptor ubiquitination and accelerated intracellular degradation. .

Gene Information

Mouse
Gene Name:	Lrig1
Uniprot:	P70193
Entrez:	16206

Family

Belongs to:

No superfamily

Alternative Names

D6Bwg0781e; Img; LIG1; LIG-1; LRIG1

Molecular Weight

Mass (kDA):
119.156 kDA

Genomic Context


Mouse

Location:	6 D2\|6 43.15 cM
Sequence:	6;

Tissue Specificity

Detected in brain (at protein level) (PubMed:12067728). Predominantly expressed in the brain, restricted to a small subset of glial cells, such as Bergmann glial cells of the cerebellum and glial cells in the nerve fiber layer of the olfactory bulb. Expressed also in the skin. Low expression is detected in the thymus and heart. No expression in the kidney, liver, lung or small intestine.

Diseases

Neoplasms
Malignant Neoplasms
Carcinoma
Cell Invasion
Cell Transformation, Neoplastic
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Breast
Glioma
Mammary Neoplasms
Malignant Squamous Cell Neoplasm
Brain Neoplasms
Malignant Neoplasm Of Urinary Bladder

Tissue Adhesions
Hyperplasia
Neoplasm Invasiveness
Malignant Tumor Of Cervix
Astrocytoma
Adenocarcinoma
Uterine Cervical Neoplasm

Pathways

Cell Proliferation
Cell Growth
Cell Cycle
Pathogenesis
Oncogenesis
Localization
Cell Adhesion
Cell-cell Adhesion
Tissue Morphogenesis
Rna Interference
Inner Ear Morphogenesis
Cell Migration
Keratinocyte Activation

Gene Silencing
Stem Cell Maintenance
Immune Response
Cell Fate Determination
Ear Morphogenesis
Cell Division
Tissue Development

PTMs

Phosphorylation
Biotinylation
Glycosylation

Cleavage
Acetylation
Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Lrig1

References

PMID: 8798419 by Suzuki Y., et al. cDNA cloning of a novel membrane glycoprotein that is expressed specifically in glial cells in the mouse brain. LIG-1, a protein with leucine-rich repeats and immunoglobulin-like domains.

PMID: 12067728 by Suzuki Y., et al. Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia.