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Lipoprotein lipase Antibodies
AND LPL ELISA kits, Lipoprotein lipase Proteins
Many biological assays use antibodies to detect Lipoprotein lipase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lipoprotein lipase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lipoprotein lipase antibodies...
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LPL Infographic by Boster Bio
All LPL Products
Product
Figures
Specificity
Applications
Price
Anti-Lipoprotein lipase LPL Rabbit Monoclonal Antibody
2 Citations 1 Q&As
Human
IHC, WB
$370
Cat # M00316
100 μl
Cat # M00316
100 μl
Human
$250
Cat # PROTP06858
2ug, 10ug, 1mg
Cat # PROTP06858
2ug, 10ug, 1mg
Human, Mouse, Rat
IF, IHC, WB
$523
Cat # M00316-1
100 µl
Cat # M00316-1
100 µl
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$523
Cat # M00316-2
100 µl
Cat # M00316-2
100 µl
LPL Overview
Facts about Lipoprotein lipase.
Lipoprotein lipase (LPL)
The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL) (PubMed:27578112). Binding to heparin sulfate proteogylcans at the cell surface is vital to the function.
The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the luminal surface of vascular endothelium (By similarity). .
Gene Information
| Human | |
|---|---|
| Gene Name: | LPL |
| Uniprot: | P06858 |
| Entrez: | 4023 |
Family
| Belongs to: |
|---|
| AB hydrolase superfamily |
Alternative Names
EC 3.1.1; HDLCQ11; LIPD; LIPDEC 3.1.1.34; Lipoprotein Lipase; LPL
Molecular Weight
Mass (kDA):
53.162 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8p21.3 |
| Sequence: | 8; NC_000008.11 (19939253..19967259) |
Subcellular Localizations
Cell membrane; Peripheral membrane protein; Extracellular side. Secreted. Secreted, extracellular space, extracellular matrix. Newly synthesized LPL binds to cell surface heparan proteoglycans and is then released by heparanase. Subsequently, it becomes attached to heparan proteoglycan on endothelial cells (PubMed:27811232). Locates to the plasma membrane of microvilli of hepatocytes with triglyceride-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non-coated endocytic vesicles (By similarity).
Diseases
- Obesity
- Diabetes Mellitus
- Hyperlipidemia
- Atherosclerosis
- Insulin Resistance
- Hyperlipoproteinemia Type I
- Diabetes Mellitus, Non-insulin-dependent
- Coronary Heart Disease
- Dyslipidemias
- Cardiovascular Diseases
- Neoplasms
- Malignant Neoplasms
- Heart Diseases
Pathways
- Secretion
- Transport
- Pathogenesis
- Localization
- Lactation
- Cell Proliferation
- Cell Differentiation
- Translation
- Insulin Secretion
- Immune Response
- Cholesterol Transport
- Glycosylation
- Aging
PTMs
- Oxidation
- Phosphorylation
- Glycosylation
- Cleavage
- Acylation
- Methylation
- Biotinylation
- Reduction
- Acetylation
- Sulphation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LPL
bosterbio.com/bosterbio-gene-info-cards/LPL
References
PMID: 3823907 by Wion K.L., et al. Human lipoprotein lipase complementary DNA sequence.
PMID: 2701938 by Gotoda T., et al. Nucleotide sequence of human cDNA coding for a lipoprotein lipase (LPL) cloned from placental cDNA library.
2 Publications of Boster Lipoprotein lipase Antibodies & ELISA Kits
- PubMed ID: 30456017, Supplemental Information
- PubMed ID: 21762526, Liu Y, Wang Zb, Yin Wd, Li Qk, Cai Mb, Yu J, Li Hg, Zhang C, Zu Xh. Lipids Healt...
*More publications can be found for each product on its corresponding product page