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LMX1A Antibodies

AND LMX1A ELISA kits, LMX1A Proteins

Many biological assays use antibodies to detect LMX1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LMX1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LMX1A antibodies...

We validate the specificity of these antibodies to LMX1A by testing them on tissues known to express LMX1A positively and negatively. Browse below to find the LMX1A antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LMX1A Infographic by Boster Bio

LMX1A protein infographic

All LMX1A Products

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Product

Figures

Specificity

Applications

Price

Anti-LMX1A Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, ICC, WB

$449
Cat # A06287
0.1 mg

LMX1A (NM_177398) Human Over-expression Lysate

Human

$628
Cat # LS004009
100 µg

LMX1A Overview

Facts about LIM homeobox transcription factor 1-alpha.

LMX1A 3D structure

LMX1A 3D structure. Source: alphafold

LIM homeobox transcription factor 1-alpha (LMX1A)

Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and growing vertebrae (By similarity).

. .

Gene Information

Human
Gene Name:	LMX1A
Uniprot:	Q8TE12
Entrez:	4009

Gene Information

Family

Belongs to:

No superfamily

Family

Alternative Names

LIM homeobox transcription factor 1, alpha; LMX1.1

Molecular Weight

Mass (kDA):
42.747 kDA

Molecular Weight

Genomic Context


Human

Location:	1q23.3
Sequence:	1; NC_000001.11 (165201867..165356715, complement)

Subcellular Localizations

Nucleus.

Subcellular Localization

Diseases

Parkinson Disease
Malignant Neoplasms
Neoplasms
Nervousness
Malignant Tumor Of Cervix
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Nervous System Disorder
Hemorrhage
Neurodegenerative Disorders
Neoplasm Metastasis
Neoplasm Invasiveness
Carcinoma

Cervical Intraepithelial Neoplasia
Refractory Neutropenia
Lesch-nyhan Syndrome
Idiopathic Hypereosinophilic Syndrome
Hypoplasia
Uterine Cervical Neoplasm
Secondary Parkinson Disease

Disease

Interacting Proteins

GRB2

Interacting Proteins

Pathways

Neurogenesis
Methylation
Limb Development
Roof Plate Formation
Neuron Development
Cell Cycle
Dna Methylation
Pathogenesis
Localization
Midbrain Development
Pigmentation
Cell Differentiation
Neuron Differentiation

Neural Tube Closure
Cell Migration
Inner Ear Morphogenesis
Brain Development
Lung Development
Cell Fate Determination
Inner Ear Development

Pathways

PTMs

Methylation

Reduction

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LMX1A

References

PMID: 12062816 by Thameem F., et al. Cloning, expression and genomic structure of human LMX1A, and variant screening in Pima Indians.