Lamin-B1 Antibodies

AND LMNB1 ELISA kits, Lamin-B1 Proteins

Many biological assays use antibodies to detect Lamin-B1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lamin-B1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lamin-B1 antibodies...

We validate the specificity of these antibodies to Lamin-B1 by testing them on tissues known to express LMNB1 positively and negatively. Browse below to find the LMNB1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LMNB1 Infographic by Boster Bio

All LMNB1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Lamin B1/LMNB1 Antibody Picoband®

49 Citations 1 Q&As

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # PB9611
100 μg/vial

Anti-Lamin B1/LMNB1 Antibody Picoband®

24 Citations 5 Q&As

Human, Mouse, Rat

IF, IHC, IHC-F, ICC, WB

$370
Cat # PA1048
100 μg/vial

Anti-Lamin B1 LMNB1 Rabbit Monoclonal Antibody

15 Citations

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$370
Cat # M02778
100 μl

Lamin B1 (LMNB1) (NM_005573) Human Over-expression Lysate

Human

$628
Cat # LS004001
100 µg

LMNB1 Overview

Facts about Lamin-B1.

LMNB1 3D structure. Source: alphafold

Lamin-B1 (LMNB1)

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is considered to present a framework for the nuclear envelope and may also interact with chromatin. .

Gene Information

Human
Gene Name:	LMNB1
Uniprot:	P20700
Entrez:	4001

Family

Belongs to:

intermediate filament family

Alternative Names

ADLD; Lamin B1; lamin-B1; LMN; LMN2; LMNB; LMNB1; MGC111419

Molecular Weight

Mass (kDA):
66.408 kDA

Genomic Context


Human

Location:	5q23.2
Sequence:	5; NC_000005.10 (126776623..126837020)

Subcellular Localizations

Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side.

Diseases

Leukodystrophy
Malignant Neoplasms
Muscular Dystrophy, Emery-dreifuss
Neoplasms
Lipodystrophy
Sclerosis
Carcinoma
Dystrophy
Muscular Dystrophy
Dysplasia
Liver Carcinoma
Colorectal Cancer

Familial Partial Lipodystrophy
Colorectal Neoplasms
Liver Neoplasms
Progeria
Multiple Sclerosis
X-linked Emery-dreifuss Muscular Dystrophy

Interacting Proteins

KPNA1
LMNA
LMNB2
MAP1LC3B
PIH1D2

Pathways

Dna Replication
Aging
Localization
Myelination
Chromatin Organization
Cell Proliferation
Cell Growth
Transport
Brain Development
Regulation Of Gene Expression
Cell Cycle Arrest
Reverse Transcription
Myelin Maintenance

Translation
Cell Cycle
Cellular Response To Stress
Oligodendrocyte Development
Lymphocyte Proliferation
Oligodendrocyte Differentiation
Response To Stress

PTMs

Phosphorylation

Farnesylation

Dephosphorylation

Research Areas

Apoptosis
Cancer
Core ESC-Like Genes
Loading Controls
Stem Cell Markers

Tumor Suppressors

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LMNB1

References

PMID: 2325650 by Pollard K.M., et al. In vitro posttranslational modification of lamin B cloned from a human T-cell line.

PMID: 7557986 by Lin F., et al. Structural organization of the human gene (LMNB1) encoding nuclear lamin B1.

54 Publications of Boster Lamin-B1 Antibodies & ELISA Kits

PubMed ID: PMID:26191193, Clinicopathologic and prognostic significance of p21 (Cip1/Waf1) expression in b...
PubMed ID: 10.7150/ijbs.17238, Deguelin Attenuates Allergic Airway Inflammation via Inhibition of NF-κb Pathwa...
PubMed ID: 10.1186/1465-9921-11-33, Histone deacetylase inhibitor, butyrate, attenuates lipopolysaccharide-induced a...
PubMed ID: 10.1159/000479439, Lanthanum Chloride Inhibits LPS Mediated Expressions of Pro-Inflammatory Cytokin...
PubMed ID: 10.1111/jpn.13664, Chitosan nanoparticles attenuate intestinal damage and inflammatory responses in...
PubMed ID: 10.1111/j.1476-5381.2011.01505.x, Cellular pharmacokinetic mechanisms of adriamycin resistance and its modulation ...
PubMed ID: 10.1089/rej.2017.1960, Naringenin Ameliorates Behavioral Dysfunction and Neurological Deficits in a d-G...
PubMed ID: 10.1080/19768354.2021.2018043, Grub polypeptide extracts protect against oxidative stress through the NRF2-ARE ...
PubMed ID: 10.1080/1354750X.2016.1217933, Aberrant methylation of nucleotide excision repair genes is associated with chro...
PubMed ID: 10.1039/D1FO02579A, Diosmetin alleviated cerebral ischemia/reperfusion injury in vivo and in vitro b...
PubMed ID: 10.1039/C7RA11491E, α-Lipoic acid alleviates pentetrazol-induced neurological deficits and behavior...
PubMed ID: 10.1039/C6FO00825A, Myricetin alleviates cuprizone-induced behavioral dysfunction and demyelination ...
PubMed ID: 10.1038/srep30563, The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral ...
PubMed ID: 10.1038/srep30322, Simulated microgravity inhibits osteogenic differentiation of mesenchymal stem c...
PubMed ID: 10.1038/s41419-020-03064-x, PRMT5/Wnt4 axis promotes lymph-node metastasis and proliferation of laryngeal ca...
PubMed ID: 10.1038/cddis.2014.479, Activation of volume-sensitive outwardly rectifying chloride channel by ROS cont...
PubMed ID: 10.1016/j.toxlet.2017.07.215, MicroRNA-155 regulates arsenite-induced malignant transformation by targeting Nr...
PubMed ID: 10.1016/j.neuroscience.2017.05.022, NAMPT inhibitor protects ischemic neuronal injury in rat brain via anti-neuroinf...
PubMed ID: 10.1016/j.molimm.2017.06.018, Macrophages induce EMT to promote invasion of lung cancer cells through the IL-6...
PubMed ID: 10.1016/j.ejphar.2017.12.019, Klotho upregulation contributes to the neuroprotection of ligustilide against ce...
PubMed ID: 10.1016/j.bbrc.2017.08.089, Procyanidin B2 ameliorates carrageenan-induced chronic nonbacterial prostatitis ...

*Showing only the more recent 20. More publications can be found for each product on its corresponding product page