Protein ERGIC-53 Antibodies

Protein ERGIC-53 (LMAN1)

Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both.

The LMAN1-MCFD2 complex forms a specific cargo receptor to the ER-to-Golgi transport of selected proteins. .

Gene Information

Human
Gene Name:	LMAN1
Uniprot:	P49257
Entrez:	3998

Family

Belongs to:
No superfamily

Alternative Names

ERGIC-53; ERGIC53ER-Golgi intermediate compartment 53 kDa protein; F5F8Dendoplasmic reticulum-golgi intermediate compartment protein 53; FMFD1; Gp58; intracellular mannose specific lectin; Intracellular mannose-specific lectin MR60; Lectin mannose-binding 1; lectin, mannose-binding, 1; MCFD1coagulation factor V-factor VIII combined deficiency; MR60; protein ERGIC-53

Molecular Weight

Mass (kDA):
57.549 kDA

Genomic Context

Human
Location:	18q21.32
Sequence:	18; NC_000018.10 (59327823..59359265, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.

Diseases

• Factor V Deficiency
• Hemophilia A
• Hemorrhage
• Bleeding Tendency
• Familial Multiple Factor Deficiency Syndrome, Type I
• Blood Coagulation Disorders
• Coagulation Factor Deficiency
• Vesicular Stomatitis
• Stomatitis
• Blood Coagulation Disorders, Inherited
• Hemorrhagic Disorders
• Spots On Skin

• Alzheimer's Disease
• Endoplasmic Reticulum Stress
• Contusions
• Hereditary Diseases
• Congenital Disorders Of Glycosylation
• Congenital Disorders
• Classical Galactosemia

Interacting Proteins

• ERP44
• MCFD2
• SURF4

Pathways

• Transport
• Secretory Pathway
• Coagulation
• Localization
• Secretion
• Glycosylation
• Intracellular Transport
• Protein Transport
• Blood Coagulation
• Translation
• Mitosis
• Rna Interference
• Microtubule Depolymerization

• Regeneration
• Protein Folding
• Pathogenesis
• Cell Cycle
• Hemostasis
• Autophagy
• Protein Unfolding

PTMs

• Glycosylation
• Phosphorylation
• Biotinylation
• Cleavage

• Amination
• Ribosylation
• Ubiquitination
• Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LMAN1

Best Uses Of The LMAN1 Marker

Boster Bio has a monoclonal antibody that can be used against the LMAN1 Gene. This antibody has been validated for Western Blotting, Immunohistochemistry, and ELISA. It is highly reactive against LMAN1 genes and has excellent affinity for the corresponding Ligand. Boster also makes other useful antibodies like pA4, PCDNA3, or p-ChIP.

Boster Bio Anti-LMAN1 Antibody

The Boster Bio Anti-LMAN1 Antibodies are monoclonal or polyclonal antibodies with high affinity. These antibodies were validated on IHC and WB. These antibodies have been used in scientific research for 25+ years. The Boster Anti-LMAN1 Antibody was developed by leading experts in bioinformatics, immunohistochemistry and cell biology.

Boster Bio Anti KHDRBS2 Antibody

Boster Bio Anti-KHDRBS2-KHDRBS2 is a monoclonal antibody that reacts with Khdrbs2 protein in various samples, including cells and particles. This antibody is designed to react with Human, Mouse and Rat cells, as well as other species. The Boster bio Anti-KHDRBS2-KHDRBS2 Antibody is available as a 100ul Liquid antibody.

Boster Bio Anti-Bax (S4) Antibody

Boster Bio Anti-Bax A00183 antibody was validated in a rat and mouse lymphocyte model. It reacts with LMAN1 marker. It is also available in 100-ul Liquid. This antibody has been validated by Western Blotting, Immunohistochemistry, and ELISA. It is a highly specific and highly effective monoclonal antibody that detects a wide range of samples, including those that are known to be negative.