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Protein ERGIC-53 Antibodies
AND LMAN1 ELISA kits, Protein ERGIC-53 Proteins
Many biological assays use antibodies to detect Protein ERGIC-53, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein ERGIC-53 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein ERGIC-53 antibodies...
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LMAN1 Infographic by Boster Bio
All LMAN1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A03628-1
100 μg/vial
Cat # A03628-1
100 μg/vial
Dog, Human, Monkey, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M03628-2
100 µl
Cat # M03628-2
100 µl
Dog, Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M03628
100 µl
Cat # M03628
100 µl
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M03628-3
100 μl/vial
Cat # M03628-3
100 μl/vial
LMAN1 Overview
Facts about Protein ERGIC-53.
Protein ERGIC-53 (LMAN1)
Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both.
The LMAN1-MCFD2 complex forms a specific cargo receptor to the ER-to-Golgi transport of selected proteins. .
Gene Information
| Human | |
|---|---|
| Gene Name: | LMAN1 |
| Uniprot: | P49257 |
| Entrez: | 3998 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
ERGIC-53; ERGIC53ER-Golgi intermediate compartment 53 kDa protein; F5F8Dendoplasmic reticulum-golgi intermediate compartment protein 53; FMFD1; Gp58; intracellular mannose specific lectin; Intracellular mannose-specific lectin MR60; Lectin mannose-binding 1; lectin, mannose-binding, 1; MCFD1coagulation factor V-factor VIII combined deficiency; MR60; protein ERGIC-53
Molecular Weight
Mass (kDA):
57.549 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 18q21.32 |
| Sequence: | 18; NC_000018.10 (59327823..59359265, complement) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Diseases
- Factor V Deficiency
- Hemophilia A
- Hemorrhage
- Bleeding Tendency
- Familial Multiple Factor Deficiency Syndrome, Type I
- Blood Coagulation Disorders
- Coagulation Factor Deficiency
- Vesicular Stomatitis
- Stomatitis
- Blood Coagulation Disorders, Inherited
- Hemorrhagic Disorders
- Spots On Skin
Interacting Proteins
- ERP44
- MCFD2
- SURF4
Pathways
- Transport
- Secretory Pathway
- Coagulation
- Localization
- Secretion
- Glycosylation
- Intracellular Transport
- Protein Transport
- Blood Coagulation
- Translation
- Mitosis
- Rna Interference
- Microtubule Depolymerization
PTMs
- Glycosylation
- Phosphorylation
- Biotinylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LMAN1
bosterbio.com/bosterbio-gene-info-cards/LMAN1
References
PMID: 8223692 by Schindler R., et al. ERGIC-53, a membrane protein of the ER-Golgi intermediate compartment, carries an ER retention motif.
PMID: 7876089 by Arar C., et al. ERGIC-53, a membrane protein of the endoplasmic reticulum-Golgi intermediate compartment, is identical to MR60, an intracellular mannose-specific lectin of myelomonocytic cells.