LILRB3 Antibodies

AND LILRB3 ELISA kits, LILRB3 Proteins

Many biological assays use antibodies to detect LILRB3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LILRB3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LILRB3 antibodies...

We validate the specificity of these antibodies to LILRB3 by testing them on tissues known to express LILRB3 positively and negatively. Browse below to find the LILRB3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LILRB3 Infographic by Boster Bio

All LILRB3 Products

Product

Figures

Specificity

Applications

Price

Anti-LIRB3 LILRB3 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A07943
100ul

Anti-LILRB3 Mouse Monoclonal Antibody [Clone ID: OTI3G9]

Human

$523
Cat # M07943
100 µl

LILRB3 (NM_006864) Human Over-expression Lysate

Human

$628
Cat # LS011025
100 µg

LILRB3 Overview

Facts about Leukocyte immunoglobulin-like receptor subfamily B member 3.

LILRB3 3D structure. Source: alphafold

Leukocyte immunoglobulin-like receptor subfamily B member 3 (LILRB3)

May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor.

Down-regulates antigen-induced B- cell activation by recruitment phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM). .

Gene Information

Human
Gene Name:	LILRB3
Uniprot:	O75022
Entrez:	11025

Family

Belongs to:

No superfamily

Alternative Names

CD85 antigen-like family member A; CD85a antigen; CD85a; HL9Immunoglobulin-like transcript 5; ILT5; ILT-5; ILT5CD85a; Leukocyte immunoglobulin-like receptor 3; leukocyte immunoglobulin-like receptor subfamily B member 3; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains); LILRB3; LIR3; LIR3CD85A; LIR-3MGC138403; member 3; Monocyte inhibitory receptor HL9; PIRB

Molecular Weight

Mass (kDA):
69.386 kDA

Genomic Context


Human

Location:	19q13.42
Sequence:	19; NC_000019.10 (54216278..54223087, complement)

Tissue Specificity

Detected in monocytes and B-cells.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Arthritis
Inflammation
Neoplasm Metastasis
Collagen Diseases
Primary Neoplasm
Metastatic Malignant Neoplasm To The Lung
Thymus Neoplasms
Neurodegenerative Disorders
Graft-vs-host Disease
Carcinogenesis
Malignant Neoplasms
Neoplasms

Hiv Infections
Nervousness
Lymphoma
Osteoporosis
Thymic Lymphoma
Rheumatoid Arthritis

Interacting Proteins

KRT18
KRT8
PTPN6

Pathways

Osteoclast Development
Cell Migration
Cell Proliferation
T Cell Migration
Cell Cycle
T Cell Proliferation
Dna Repair

Bone Resorption
Secretion

PTMs

Disulfide bond

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LILRB3

References

PMID: 9278324 by Arm J.P., et al. Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor.

PMID: 9548455 by Borges L., et al. A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules.