LIFR Antibodies

AND LIFR ELISA kits, LIFR Proteins

Many biological assays use antibodies to detect LIFR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LIFR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LIFR antibodies...

We validate the specificity of these antibodies to LIFR by testing them on tissues known to express LIFR positively and negatively. Browse below to find the LIFR antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LIFR Infographic by Boster Bio

All LIFR Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-LIFR Antibody Picoband®

1 Q&As

Human

$370
Cat # PB9661
100 μg/vial

Human LIFR/Lif R Alpha ELISA Kit PicoKine®

5 Q&As

Human

ELISA

$750
Cat # EK1200
96 wells/kit, with removable strips.

Human LIF R alpha Recombinant Protein

SDS-PAGE

$250
Cat # PROTP42702
Starting from 10ug

LIFR Overview

Facts about Leukemia inhibitory factor receptor.

LIFR 3D structure. Source: alphafold

Leukemia inhibitory factor receptor (LIFR)

Signal-transducing molecule. May have a common pathway with IL6ST.

The soluble form inhibits the biological action of LIF by blocking its binding to receptors on target cells. .

Gene Information

Human
Gene Name:	LIFR
Uniprot:	P42702
Entrez:	3977

Family

Belongs to:

type I cytokine receptor family

Alternative Names

CD118 antigen; CD118; FLJ98106; FLJ99923; leukemia inhibitory factor receptor alpha; leukemia inhibitory factor receptor; LIF R alpha; LIF R beta; LIF receptor; LIFR alpha; LIFR; LIF-R; LIFRa; SJS2; STWS; SWS

Molecular Weight

Mass (kDA):
123.743 kDA

Genomic Context


Human

Location:	5p13.1
Sequence:	5; NC_000005.10 (38474668..38606290, complement)

Subcellular Localizations

[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.

Diseases

Leukemia
Neoplasms
Inflammation
Nervousness
Malignant Neoplasms
Janiceps
Endometrial Polyp
Carcinoma
Liver Carcinoma
Hypertrophy
Neuroblastoma
Pituitary Diseases
Myeloid Leukemia

Multiple Myeloma
Malignant Paraganglionic Neoplasm
Choriocarcinoma
Infertility
Malignant Neoplasm Of Breast
Mammary Neoplasms
Chimera Disorder

Interacting Proteins

CNTF

Pathways

Secretion
Cell Growth
Cell Proliferation
Regeneration
Cell Differentiation
Cell Death
Embryo Development
Localization
Pathogenesis
Embryo Implantation
Neurogenesis
Inflammatory Response
Reverse Transcription

Bone Resorption
Cell Cycle
Macrophage Differentiation
Osteoblast Differentiation
System Development
Decidualization
Cell Adhesion

PTMs

Phosphorylation
Methylation
Glycosylation
Cleavage

Acetylation
Iodination
Demethylation
Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LIFR

References

PMID: 1915266 by Gearing D.P., et al. Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130.

PMID: 9525740 by Voz M.L., et al. The recurrent translocation t(5;8)(p13;q12) in pleomorphic adenomas results in upregulation of PLAG1 gene expression under control of the LIFR promoter.