LIM/homeobox protein Lhx3 Antibodies

AND LHX3 ELISA kits, LIM/homeobox protein Lhx3 Proteins

Many biological assays use antibodies to detect LIM/homeobox protein Lhx3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LIM/homeobox protein Lhx3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LIM/homeobox protein Lhx3 antibodies...

We validate the specificity of these antibodies to LIM/homeobox protein Lhx3 by testing them on tissues known to express LHX3 positively and negatively. Browse below to find the LHX3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LHX3 Infographic by Boster Bio

All LHX3 Products

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Product

Figures

Specificity

Applications

Price

Anti-LHX3 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IP, WB

$370
Cat # M03803
100 μl/vial

LHX3 (NM_178138) Human Over-expression Lysate

Human

$628
Cat # LS008022
100 µg

LHX3 Overview

Facts about LIM/homeobox protein Lhx3.

LHX3 3D structure. Source: alphafold

LIM/homeobox protein Lhx3 (LHX3)

Acts as a transcriptional activator. Binds to and activates the promoter of this alpha-glycoprotein gene, and synergistically enhances transcription from the prolactin promoter in collaboration with POU1F1/Pit-1 (By similarity).

Required for the establishment of the specialized cells of the pituitary gland and the nervous system. Involved in the development of interneurons and motor neurons in collaboration with LDB1 and ISL1.

Gene Information

Human
Gene Name:	LHX3
Uniprot:	Q9UBR4
Entrez:	8022

Family

Belongs to:

No superfamily

Alternative Names

CPHD3; DKFZp762A2013; LIM homeobox 3; LIM homeobox protein 3; LIM/homeobox protein Lhx3; LIM/homeodomain protein LHX3; LIM3; M2-LHX3

Molecular Weight

Mass (kDA):
43.358 kDA

Genomic Context


Human

Location:	9q34.3
Sequence:	9; NC_000009.12 (136196250..136205128, complement)

Subcellular Localizations

Nucleus.

Diseases

Pituitary Diseases
Hypopituitarism
Nervousness
Hypoplasia
Dysplasia
Septo-optic Dysplasia
Dwarfism
Somatotropin Deficiency
Pituitary Gland Hypoplasia
Deficiency Diseases
Neoplasms
Holoprosencephaly

Hypothyroidism
Growth Disorders
Adrenocorticotropic Hormone (acth) Deficiency (disorder)
Infertility
Hypoglycemia
Secondary Hypothyroidism
Malignant Neoplasms

Interacting Proteins

CSNK2A1

Pathways

Secretion
System Development
Localization
Nervous System Development
Cell Differentiation
Pathogenesis
Pituitary Gland Development
Gland Development
Neuron Development
Cell Death
Inner Ear Development
Translation
Gastrulation

Cell Proliferation
Ear Development
Axon Guidance
Lactation
Locomotion
Transport
Cell Migration

PTMs

Phosphorylation

Cleavage

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LHX3

References

PMID: 10598593 by Sloop K.W., et al. Differential activation of pituitary hormone genes by human Lhx3 isoforms with distinct DNA binding properties.

PMID: 15517599 by Parker G.E., et al. Serine/threonine/tyrosine phosphorylation of the LHX3 LIM-homeodomain transcription factor.