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, No Gclids
Galectin-3 Antibodies
AND LGALS3 ELISA kits, Galectin-3 Proteins
Many biological assays use antibodies to detect Galectin-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Galectin-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Galectin-3 antibodies...
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LGALS3 Infographic by Boster Bio
All LGALS3 Products
Product
Figures
Specificity
Applications
Price
Human Galectin-3/LGALS3 ELISA Kit PicoKine®
9 Citations 9 Q&As
Human
ELISA
$499
Cat # EK0764
96 wells/kit, with removable strips.
Cat # EK0764
96 wells/kit, with removable strips.
Mouse Galectin-3/LGALS3 ELISA Kit PicoKine®
2 Citations 6 Q&As
Mouse
ELISA
$499
Cat # EK0765
96 wells/kit, with removable strips.
Cat # EK0765
96 wells/kit, with removable strips.
Anti-Galectin 3/LGALS3 Antibody Picoband®
4 Citations
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9081
100 μg/vial
Cat # PB9081
100 μg/vial
Human, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M00621
100 μl
Cat # M00621
100 μl
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00621-3
100 μg/vial
Cat # M00621-3
100 μg/vial
Human, Mouse, Rat
ELISA
$480
Cat # EKC1233
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1233
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00621-4
100 μl/vial
Cat # M00621-4
100 μl/vial
LGALS3 Overview
Facts about Galectin-3.
Galectin-3 (LGALS3)
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration.
Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). From the nucleus: functions as a pre-mRNA splicing factor.
Gene Information
| Human | |
|---|---|
| Gene Name: | LGALS3 |
| Uniprot: | P17931 |
| Entrez: | 3958 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
AGE-R3; Carbohydrate-binding protein 35; CBP 35,35 kDa lectin; CBP35; GAL3; Gal-3; galactin-3; Galactose-specific lectin 3; Galactoside-binding protein; GALBPCBP35; Galectin3; Galectin-3; GALIG; IgE-binding protein; L29; L31; L-31; Laminin-binding protein; Lectin L-29; lectin, galactoside-binding, soluble, 3; LGALS2; LGALS3; Mac-2 antigen; Mac-2; MAC2GAL3
Molecular Weight
Mass (kDA):
26.152 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q22.3 |
| Sequence: | 14; NC_000014.9 (55129252..55145430) |
Tissue Specificity
A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes.
Subcellular Localizations
Cytoplasm. Nucleus. Secreted. Secreted by a non-classical secretory pathway and associates with the cell surface.
Diseases
- Neoplasms
- Malignant Neoplasms
- Inflammation
- Tissue Adhesions
- Carcinoma
- Thyroid Neoplasm
- Fibrosis
- Adenoma
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Thyroid
- Carcinoma, Papillary
- Atherosclerosis
- Neoplasm Metastasis
Interacting Proteins
- ALCAM
- CD6
- CHI3L1
- GOLGA2
- IL13RA2
- MICA
- MMP7
- NCR3
- PDCD6IP
- PPIG
Pathways
- Pathogenesis
- Immune Response
- Cell Proliferation
- Cell Adhesion
- Dna Methylation
- Methylation
- Cell Growth
- Angiogenesis
- Inflammatory Response
- Cell Migration
- Macrophage Activation
- Transport
- Cell Death
PTMs
- Phosphorylation
- Methylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LGALS3
bosterbio.com/bosterbio-gene-info-cards/LGALS3
References
PMID: 2261464 by Robertson M.W., et al. Human IgE-binding protein: a soluble lectin exhibiting a highly conserved interspecies sequence and differential recognition of IgE glycoforms.
PMID: 2402511 by Cherayil B., et al. Molecular cloning of a human macrophage lectin specific for galactose.
14 Publications of Boster Galectin-3 Antibodies & ELISA Kits
- PubMed ID: 10.3892/etm.2019.7227, Expression of galectin‑3 and apoptosis in placental villi from patients with m...
- PubMed ID: 10.3390/diagnostics11112101, The Interplay between Myocardial Fibrosis, Strain Imaging and Collagen Biomarker...
- PubMed ID: 10.3389/fimmu.2021.639260, Galectin-Receptor Interactions Regulates Cardiac Pathology Caused by Trichine...
- PubMed ID: 10.1155/2021/3210586, Insulin Receptor Substrate p53 Ameliorates High-Glucose-Induced Activation of NF...
- PubMed ID: 10.1080/14767058.2019.1637409, Maternal serum galectin-1 and galectin-3 levels in pregnancies complicated with ...
- PubMed ID: 10.1016/j.jash.2017.07.009, Galectin-3 mediates pulmonary vascular remodeling in hypoxia-induced pulmonary a...
- PubMed ID: 10.1016/j.ajg.2021.03.002, Comparison between galectin-3 and YKL-40 levels for the assessment of liver fibr...
- PubMed ID: 10.1007/s11126-020-09731-8, Galectin-1 and Galectin-3 Levels in Patients with Schizophrenia and their Unaffe...
- PubMed ID: 10.1007/s00394-011-0194-3, Modified apple polysaccharide prevents against tumorigenesis in a mouse model of...
- PubMed ID: -, Dadarlat-Pop A,Pop D,Procopciuc L,Sitar-Taut A,Zdrenghea D,Bodizs G,Tomoaia R,Gu...
- PubMed ID: 31767078 , Cofilin-1, peroxiredoxin-1, and galectin-3: Major proteins released by macrophag...
- PubMed ID: 30778007, Clinical significance of galectin-3 expression in malformed hepatic venous tissu...
- PubMed ID: 28974104 , Prospective Validation of a Screening Biomarker Approach Combining Amino-Termina...
- PubMed ID: 26787685 , Predictive Value for Galectin 3 and Cardiotrophin 1 in Hemodialysis Patients
*More publications can be found for each product on its corresponding product page