LCT Antibodies

AND LCT ELISA kits, LCT Proteins

Many biological assays use antibodies to detect LCT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LCT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LCT antibodies...

We validate the specificity of these antibodies to LCT by testing them on tissues known to express LCT positively and negatively. Browse below to find the LCT antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LCT Infographic by Boster Bio

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LCT Overview

Facts about Lactase-phlorizin hydrolase.

LCT 3D structure. Source: alphafold

Lactase-phlorizin hydrolase (LCT)

LPH splits lactose in the small intestine. .

Gene Information

Human
Gene Name:	LCT
Uniprot:	P09848
Entrez:	3938

Family

Belongs to:

glycosyl hydrolase 1 family

Alternative Names

EC 3.2.1; LAC; lactase; Lactase-glycosylceramidase; lactase-phlorizin hydrolase; LPH1; LPHlactase-phlorizin hydrolase-1

Molecular Weight

Mass (kDA):
218.587 kDA

Genomic Context


Human

Location:	2q21.3
Sequence:	2; NC_000002.12 (135787850..135837195, complement)

Tissue Specificity

Intestine.

Subcellular Localizations

Apical cell membrane; Single-pass type I membrane protein. Brush border.

Diseases

Neoplasms
Lactose Intolerance
Malignant Neoplasms
Pain
Obesity
Leydig Cell Tumor
Cholangiocarcinoma
Malabsorption Syndrome
Testicular Neoplasms
Carcinoma
Systemic Infection
Diabetes Mellitus
Alloimmunization

Malignant Paraganglionic Neoplasm
Blind Vision
Diarrhea
Inflammation
Fracture
Crohn Disease
Intestinal Diseases

Pathways

Excretion
Transport
Secretion
Phagocytosis
Pathogenesis
Inflammatory Response
Fatty Acid Oxidation
Intestinal Absorption
Localization
Gluconeogenesis
Urea Cycle
Neutrophil Activation
Cell Proliferation

Regeneration
Coagulation
Chemotaxis
Lipid Digestion
Gastric Emptying
Immune Response
Respiratory Burst

PTMs

Oxidation
Cleavage
Phosphorylation

Nitration
Reduction
Hydroxylation

Amination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LCT

References

PMID: 2460343 by Mantei N., et al. Complete primary structure of human and rabbit lactase-phlorizin hydrolase: implications for biosynthesis, membrane anchoring and evolution of the enzyme.

PMID: 1902057 by Boll W., et al. Structure of the chromosomal gene and cDNAs coding for lactase- phlorizin hydrolase in humans with adult-type hypolactasia or persistence of lactase.