Laminin subunit alpha-5 Antibodies

AND LAMA5 ELISA kits, Laminin subunit alpha-5 Proteins

Many biological assays use antibodies to detect Laminin subunit alpha-5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Laminin subunit alpha-5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Laminin subunit alpha-5 antibodies...

We validate the specificity of these antibodies to Laminin subunit alpha-5 by testing them on tissues known to express LAMA5 positively and negatively. Browse below to find the LAMA5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LAMA5 Infographic by Boster Bio

All LAMA5 Products

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Anti-LAMA5/Laminin Alpha 5 Antibody

13 Q&As

Human, Mouse

IHC

$360
Cat # A04624-1
100 µl

Anti-Laminin alpha-5 LAMA5 Antibody

Human, Mouse

ELISA, IHC, WB

$380
Cat # A04624
100ul

LAMA5 Overview

Facts about Laminin subunit alpha-5.

Laminin subunit alpha-5 (LAMA5)

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. .

Gene Information

Human
Gene Name:	LAMA5
Uniprot:	O15230
Entrez:	3911

Family

Belongs to:

No superfamily

Alternative Names

KIAA0533; KIAA1907; laminin alpha-5 chain; laminin subunit alpha-5; laminin, alpha 5; Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha

Molecular Weight

Mass (kDA):
399.737 kDA

Genomic Context


Human

Location:	20q13.33
Sequence:	20; NC_000020.11 (62309060..62367318, complement)

Tissue Specificity

Expressed in heart, lung, kidney, skeletal muscle, pancreas, retina and placenta. Little or no expression in brain and liver.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix, basement membrane. Major component.

Diseases

Tissue Adhesions
Glioblastoma
Proteinuria Of Undiagnosed Cause
Nephrotic Syndrome
Kidney Failure
Kidney Diseases
Malignant Neoplasms
Exencephaly
Polycystic Kidney Diseases
Cholangiocarcinoma
Disease Of Adrenal Medulla
Malignant Tumor Of Cervix

Intestinal Diseases
Tumor Angiogenesis
Neoplasms
Celiac Disease
Retinal Diseases
Renal Glomerular Disease

Pathways

Pathogenesis
Cell Adhesion
Lung Development
Wound Healing
Cell Proliferation
Glomerular Filtration
Cell Growth
Neural Tube Closure
Hair Follicle Development
Cell Activation
Osteoblast Differentiation
Neutrophil Extravasation
Immune Response

Vasculogenesis
Inflammatory Response
Cell Maturation
Swimming
Cell Cycle
Cell Differentiation
Epithelial Cell Differentiation

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LAMA5

References

PMID: 11821406 by Doi M., et al. Recombinant human laminin-10 (alpha5beta1gamma1). Production, purification, and migration-promoting activity on vascular endothelial cells.

PMID: 9271224 by Durkin M.E., et al. Tissue-specific expression of the human laminin alpha5-chain, and mapping of the gene to human chromosome 20q13.2-13.3 and to distal mouse chromosome 2 near the locus for the ragged (Ra) mutation.