Laminin subunit alpha-2 Antibodies

AND LAMA2 ELISA kits, Laminin subunit alpha-2 Proteins

Many biological assays use antibodies to detect Laminin subunit alpha-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Laminin subunit alpha-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Laminin subunit alpha-2 antibodies...

We validate the specificity of these antibodies to Laminin subunit alpha-2 by testing them on tissues known to express LAMA2 positively and negatively. Browse below to find the LAMA2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LAMA2 Infographic by Boster Bio

All LAMA2 Products

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Anti-Laminin 2 alpha/LAMA2 Antibody Picoband®

13 Citations 6 Q&As

Human, Mouse, Rat

$370
Cat # PA2160
100 μg/vial

Anti-Laminin alpha-2 LAMA2 Antibody

Human, Mouse

ELISA, IF, IHC

$380
Cat # A03287
100ul

LAMA2 Overview

Facts about Laminin subunit alpha-2.

Laminin subunit alpha-2 (LAMA2)

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. .

Gene Information

Human
Gene Name:	LAMA2
Uniprot:	P24043
Entrez:	3908

Family

Belongs to:

No superfamily

Alternative Names

LAMA2; Laminin alpha 2; Laminin M chain; laminin subunit alpha-2; laminin, alpha 2; Laminin-12 subunit alpha; Laminin-2 subunit alpha; LAMM; LAMMLaminin-4 subunit alpha; Merosin heavy chain; Merosin

Molecular Weight

Mass (kDA):
343.905 kDA

Genomic Context


Human

Location:	6q22.33
Sequence:	6; NC_000006.12 (128883138..129516566)

Tissue Specificity

Placenta, striated muscle, peripheral nerve, cardiac muscle, pancreas, lung, spleen, kidney, adrenal gland, skin, testis, meninges, choroid plexus, and some other regions of the brain; not in liver, thymus and bone.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix, basement membrane. Major component.

Diseases

Muscular Dystrophy
Dystrophy
Congenital Muscular Dystrophy (disorder)
Coronary Microvascular Disease
Weakness
Merosin Deficient Congenital Muscular Dystrophy
Muscle Weakness
Muscular Dystrophy, Animal
Muscle Hypotonia
Nervousness
Muscle Contracture
Neuromuscular Diseases

Myopathy
Muscular Dystrophies, Limb-girdle
Muscular Dystrophy, Duchenne
Hypertrophy
Tissue Adhesions
Fibrosis

Pathways

Pathogenesis
Cell Death
Regeneration
Glycosylation
Muscle Hypertrophy
Secretion
Schwann Cell Differentiation
Cell Differentiation
Mrna Processing
Cell Proliferation
Localization
Myoblast Proliferation
Brain Development

Fertilization
Immune Response
Proteolysis
Muscle Contraction
Myelination
Muscle Attachment
Basement Membrane Assembly

PTMs

Glycosylation
Cleavage

Phosphorylation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LAMA2

References

PMID: 8294519 by Vuolteenaho R., et al. Human laminin M chain (merosin): complete primary structure, chromosomal assignment, and expression of the M and A chain in human fetal tissues.

PMID: 8910357 by Zhang X., et al. Structure of the human laminin alpha2-chain gene (LAMA2), which is affected in congenital muscular dystrophy.

13 Publications of Boster Laminin subunit alpha-2 Antibodies & ELISA Kits

PubMed ID: 23500774, Guo C, Xu L, He Q, Liang T, Duan X, Li R. Food Chem Toxicol. 2013 Jun;56:436-42....
PubMed ID: 24697670, Liang S, Li Hc, Wang Yx, Wu Ss, Cai Yj, Cui Hl, Yang Yp, Ya J. Dev Growth Differ...
PubMed ID: 24452272, Gao S, Zheng Y, Cai Q, Yao W, Wang J, Zhang P, Wang X. J Mater Sci Mater Med. 20...
PubMed ID: 24069460, Zhu B, Xu T, Yuan J, Guo X, Liu D. Plos One. 2013 Sep 19;8(9):E76282. Doi: 10.13...
PubMed ID: 19958125, Chen W, Mo W, Sun K, Huang X, Zhang Yl, Song Hy. Curr Eye Res. 2009 Dec;34(12):1...
PubMed ID: 25133251, Chen Tl, Wang Hl, Liu Yh, Fang Y, Tan Rz, Zhou Ph, Zhou Q, Lv Xy. Scientificworl...
PubMed ID: 23635513, Cheng Y, Wang Y, Kang Yz, Hu Py, Gao Y, Pan Mx. Digestion. 2013;87(3):189-95. Do...
PubMed ID: 22484697, He S, Xia T, Wang H, Wei L, Luo X, Li X. Acta Biomater. 2012 Jul;8(7):2659-69. D...
PubMed ID: 25305234, Liu Y, Lu J, Li H, Wei J, Li X. Acta Biomater. 2015 Jan;11:114-25. Doi: 10.1016/...
PubMed ID: 23891771, Chen F, Wan H, Xia T, Guo X, Wang H, Liu Y, Li X. Eur J Pharm Biopharm. 2013 Nov...
PubMed ID: 25197353, Wu Y, Chen W, Guo M, He Q, Hu Y. Int J Clin Exp Pathol. 2014 Jul 15;7(8):4827-36...
PubMed ID: 23856441, Xu L, Zheng N, He Q, Li R, Zhang K, Liang T. Phytomedicine. 2013 Oct 15;20(13):1...
PubMed ID: 25063144, Lin Cy, Li Lt, Su Wt. Mater Sci Eng C Mater Biol Appl. 2014 Sep;42:474-8. Doi: 1...

*More publications can be found for each product on its corresponding product page