LAG3 Antibodies

AND LAG3 ELISA kits, LAG3 Proteins

Many biological assays use antibodies to detect LAG3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LAG3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LAG3 antibodies...

We validate the specificity of these antibodies to LAG3 by testing them on tissues known to express LAG3 positively and negatively. Browse below to find the LAG3 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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LAG3 Infographic by Boster Bio

All LAG3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-LAG3 Antibody

Human, Mouse

ELISA, IF, IHC-P, WB

$449
Cat # A02869
0.1 mg

Anti-LAG3 Monoclonal Antibody [2G8]

Human

ELISA, Flow Cytometry, IF, IHC-P, ICC, WB

$524
Cat # M02869-1
0.1 mg

Lymphocyte Activation Gene 3 (LAG3) (NM_002286) Human Recombinant Protein

$1249
Cat # PROTP18627
20 µg

Lymphocyte Activation Gene 3 (LAG3) (NM_002286) Human Over-expression Lysate

Human

$960
Cat # LS003902
100 µg

Anti-CD223 Rabbit Monoclonal Antibody

Human

IF, IHC, ICC

$370
Cat # M02869-3
100 µl/vial

LAG3 Overview

Facts about Lymphocyte activation gene 3 protein.

LAG3 3D structure. Source: alphafold

Lymphocyte activation gene 3 protein (LAG3)

Involved in lymphocyte activation. Binds to HLA class-II antigens.

Gene Information

Human
Gene Name:	LAG3
Uniprot:	P18627
Entrez:	3902

Family

Belongs to:

LAG3 family

Alternative Names

17b4 lag3; 17b4 neutralizing; 17b4; anti human lag3; LAG-3; CD223; CD223 Antigen; CD223 antigen; CD223; FDC; Human LAG3; Human LAG-3; LAG-3 17b4; LAG-3 blocking; LAG3; LAG-3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Protein FDC

Molecular Weight

Mass (kDA):
57.449 kDA

Genomic Context


Human

Location:	12p13.31
Sequence:	12; NC_000012.12 (6772483..6778455)

Subcellular Localizations

[Lymphocyte activation gene 3 protein]: Cell membrane; Single-pass type I membrane protein.; [Secreted lymphocyte activation gene 3 protein]: Secreted. Produced following cleavage of the main chain.

Diseases

Malignant Neoplasms
Autoimmune Reaction
Neoplasms
Autoimmune Diseases
Hiv Infections
Autoimmunity
Sclerosis
Inflammation
Exhaustion
Asthma
Chronic Lymphocytic Leukemia
Infective Disorder

Multiple Sclerosis
Leukemia
Lymphoid Leukemia
Acquired Immunodeficiency Syndrome
Immunologic Deficiency Syndromes
Hematologic Neoplasms
Diabetes Mellitus

Pathways

Lymphocyte Activation
Pathogenesis
Immune Response
Cell Proliferation
Cytokine Production
T Cell Proliferation
T Cell Homeostasis
Cell Activation
Aging
Neutrophil Extravasation
Complement Activation
Dendritic Cell Homeostasis
Inflammatory Response

Chemotaxis
Reverse Transcription
Cell Differentiation
Innate Immune Response
Cell Chemotaxis
Endothelial Cell Activation
T Cell Differentiation

PTMs

Phosphorylation

Acetylation

Research Areas

Adaptive Immunity
Immunology
Innate Immunity

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LAG3

References

PMID: 1692078 by Triebel F., et al. LAG-3, a novel lymphocyte activation gene closely related to CD4.

PMID: 1380059 by Baixeras E., et al. Characterization of the lymphocyte activation gene 3-encoded protein. A new ligand for human leukocyte antigen class II antigens.