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- Table of Contents
Facts about Keratocan.
Human | |
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Gene Name: | KERA |
Uniprot: | O60938 |
Entrez: | 11081 |
Belongs to: |
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small leucine-rich proteoglycan (SLRP) family |
CNA2; KERA; Keratocan; KTN; SLRR2B; SLRR2BKeratan sulfate proteoglycan keratocan
Mass (kDA):
40.509 kDA
Human | |
---|---|
Location: | 12q21.33 |
Sequence: | 12; NC_000012.12 (91050491..91058024, complement) |
Cornea (at protein level) (PubMed:10802664, PubMed:11683372). Increased expression in the stroma of keratoconus corneas (PubMed:11683372). Also detected in trachea, and in low levels, in intestine, skeletal muscle, ovary, lung and putamen (PubMed:10802664).
Secreted, extracellular space, extracellular matrix.
Boster Bio sells high-affinity primary antibody kits. Their antibodies are well-validated on Western Blotting, Immunohistochemistry, and ELISA methods, making them an excellent choice for your research. In addition to these antibodies, Boster also offers a KERA Marker, which can be used in the study of a variety of cellular processes.
To facilitate cancer immunotherapy, Boster Bio provides high-affinity primary antibodies against the Kera marker. This product targets the cellular membrane bound carcinoembryonic antibody and is highly specific to its target. The monovalent heterodimeric IgGs are available as monovalent, bispecific heterodimeric IgGs. These monovalent biochemical antibodies are highly compatible and can be used to enhance the cytotoxicity or phagocytotoxicity.
PMID: 10565548 by Tasheva E.S., et al. Structure and sequence of the gene encoding human keratocan.
PMID: 10802664 by Pellegata N.S., et al. Mutations in KERA, encoding keratocan, cause cornea plana.