This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about ER lumen protein-retaining receptor 2.
Also required for normal vesicular traffic through the Golgi. This receptor recognizes K-D-E-L.
Human | |
---|---|
Gene Name: | KDELR2 |
Uniprot: | P33947 |
Entrez: | 11014 |
Belongs to: |
---|
ERD2 family |
ELP-1(Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2; ER lumen protein retaining receptor 2; ERD2.2FLJ45532; ERD2-like protein 1; ERD-2-like protein; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2; KDEL endoplasmic reticulum protein retention receptor 2; KDEL receptor 2
Mass (kDA):
24.422 kDA
Human | |
---|---|
Location: | 7p22.1 |
Sequence: | 7; NC_000007.14 (6461089..6484152, complement) |
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Multi-pass membrane protein. Localized in the Golgi in the absence of bound proteins with the sequence motif K-D-E-L. Trafficks back to the endoplasmic reticulum together with cargo proteins containing the sequence motif K-D-E-L.
PMID: 1325562 by Lewis M.J., et al. Sequence of a second human KDEL receptor.
PMID: 1316805 by Hsu V.W., et al. A brefeldin A-like phenotype is induced by the overexpression of a human ERD-2-like protein, ELP-1.