KRT6A Antibodies

AND KRT6A ELISA kits, KRT6A Proteins

Many biological assays use antibodies to detect KRT6A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KRT6A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KRT6A antibodies...

We validate the specificity of these antibodies to KRT6A by testing them on tissues known to express KRT6A positively and negatively. Browse below to find the KRT6A antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KRT6A Infographic by Boster Bio

All KRT6A Products

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Product

Figures

Specificity

Applications

Price

Anti-Cytokeratin 6 Rabbit Monoclonal Antibody

1 Q&As

Human

IF, IHC, ICC, WB

$370
Cat # M30943-1
100 μl

Anti-Cytokeratin 6 KRT6A Antibody

Human

IF, IHC, ICC, WB

$405
Cat # A04012-1
100ul

KRT6A (NM_005554) Human Over-expression Lysate

Human

$628
Cat # LS003853
100 µg

KRT6A Overview

Facts about Keratin, type II cytoskeletal 6A.

KRT6A 3D structure. Source: alphafold

Keratin, type II cytoskeletal 6A (KRT6A)

Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration.

Participates in the regulation of epithelial migration by inhibiting the action of SRC during wound repair. .

Gene Information

Human
Gene Name:	KRT6A
Uniprot:	P02538
Entrez:	3853

Family

Belongs to:

intermediate filament family

Alternative Names

Allergen Hom s 5; CK6A; CK-6A; CK6C; CK6D; CK-6D; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; Cytokeratin-6A; Cytokeratin-6D; K6A; K6C; K6D; keratin 6A; keratin 6C; keratin 6D; keratin, epidermal type II, K6A; keratin, type II cytoskeletal 6A; Keratin-6A; KRT6C; KRT6D; Type-II keratin Kb6

Molecular Weight

Mass (kDA):
60.045 kDA

Genomic Context


Human

Location:	12q13.13
Sequence:	12; NC_000012.12 (52487176..52493257, complement)

Tissue Specificity

Constitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath.

Diseases

Pachyonychia Congenita
Thickened Nails
Carcinoma
Dermatologic Disorders
Malignant Neoplasms
Dystrophy
Palmoplantar Keratosis
Dystrophia Unguium
Neoplasms
Hypertrophy
Mammary Neoplasms
Malignant Neoplasm Of Breast

Leukokeratosis
Pachyonychia Congenita, Jadassohn Lewandowsky Type
Skin Diseases, Genetic
Malignant Neoplasm Of Lung
Hyperkeratosis
Pain
Malignant Squamous Cell Neoplasm

Interacting Proteins

CCDC85B
GOLGA2
HGS
KIFC3
KRT13

KRT15
KRT31
KRT38
KRT40
SGTA

TFIP11
TRIM23
TRIM54

Pathways

Wound Healing
Rna Interference
Keratinization
Translation
Cell Growth
Cell Adhesion
Cell Migration
Cytolysis
Cell Proliferation
Cornification
Aging

Metaphase
Keratinocyte Differentiation
Response To Interferon-gamma
Cell Cycle
Regulation Of Cell Proliferation
Cell Differentiation

PTMs

Phosphorylation

Research Areas

Cell Biology
Cellular Markers
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KRT6A

References

PMID: 7543104 by Takahashi K., et al. Cloning and characterization of multiple human genes and cDNAs encoding highly related type II keratin 6 isoforms.

PMID: 6191871 by Hanukoglu I., et al. The cDNA sequence of a type II cytoskeletal keratin reveals constant and variable structural domains among keratins.