KRT12 Antibodies

AND KRT12 ELISA kits, KRT12 Proteins

Many biological assays use antibodies to detect KRT12, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KRT12 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KRT12 antibodies...

We validate the specificity of these antibodies to KRT12 by testing them on tissues known to express KRT12 positively and negatively. Browse below to find the KRT12 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KRT12 Infographic by Boster Bio

All KRT12 Products

Product

Figures

Specificity

Applications

Price

Anti-K1C12 KRT12 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A05227
100ul

Keratin 12 (KRT12) (NM_000223) Human Recombinant Protein

$1249
Cat # PROTQ99456
20 µg

Anti-Cytokeratin 12 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M05227
100 μl/vial

KRT12 Overview

Facts about Keratin, type I cytoskeletal 12.

KRT12 3D structure. Source: alphafold

Keratin, type I cytoskeletal 12 (KRT12)

May play a special role in maintaining the normal corneal epithelial function. Together with KRT3, essential for the maintenance of corneal epithelium integrity (By similarity).

. .

Gene Information

Human
Gene Name:	KRT12
Uniprot:	Q99456
Entrez:	3859

Family

Belongs to:

intermediate filament family

Alternative Names

keratin, type I cytoskeletal 12; K12; keratin 12

Molecular Weight

Mass (kDA):
53.511 kDA

Genomic Context


Human

Location:	17q21.2
Sequence:	17; NC_000017.11 (40861303..40867223, complement)

Tissue Specificity

Cornea specific.

Diseases

Corneal Diseases
Dystrophy
Hereditary Corneal Dystrophy
Corneal Dystrophy, Juvenile Epithelial Of Meesmann
Conjunctival Diseases
Macular Corneal Dystrophy Type I
Corneal Epithelial Dystrophy
Granular Corneal Dystrophy
Tyrosine Transaminase Deficiency Disease
Photophobia

Amyloid Deposition
Blind Vision
Stevens-johnson Syndrome
Keratosis
Aniridia

Pathways

Pathogenesis
Cell Differentiation
Cell Proliferation
Cell Migration
Localization
Wound Healing
Cell Adhesion
Stem Cell Differentiation
Cellular Homeostasis
Embryo Development
Eye Morphogenesis
Flight

Cell Motility
Protein Digestion
Keratinocyte Proliferation
Epithelial Cell Differentiation
Epithelium Migration
Tissue Homeostasis
Transdifferentiation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KRT12

References

PMID: 8759347 by Nishida K., et al. A gene expression profile of human corneal epithelium and the isolation of human keratin 12 cDNA.

PMID: 9399908 by Nishida K., et al. Isolation and chromosomal localization of a cornea-specific human keratin 12 gene and detection of four mutations in Meesmann corneal epithelial dystrophy.