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- Table of Contents
Facts about Kynurenine 3-monooxygenase.
Quinolinic acid may also have an effect on NMDA receptor signaling in pancreatic beta cells, osteoblasts, pancreatic cells, and the gastrointestinal tract (Probable). .
Human | |
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Gene Name: | KMO |
Uniprot: | O15229 |
Entrez: | 8564 |
Belongs to: |
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aromatic-ring hydroxylase family |
KMO; kynurenine 3-monooxygenase (kynurenine 3-hydroxylase); Kynurenine 3Monooxygenase; Kynurenine 3-Monooxygenase
Mass (kDA):
55.81 kDA
Human | |
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Location: | 1q43 |
Sequence: | 1; NC_000001.11 (241531883..241595642) |
Highest levels in placenta and liver. Detectable in kidney.
Mitochondrion outer membrane; Multi-pass membrane protein.
PMID: 9237672 by Alberati-Giani D., et al. Cloning and functional expression of human kynurenine 3- monooxygenase.
PMID: 10672018 by Breton J., et al. Functional characterization and mechanism of action of recombinant human kynurenine 3-hydroxylase.