KLRF1 Antibodies

AND KLRF1 ELISA kits, KLRF1 Proteins

Many biological assays use antibodies to detect KLRF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KLRF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KLRF1 antibodies...

We validate the specificity of these antibodies to KLRF1 by testing them on tissues known to express KLRF1 positively and negatively. Browse below to find the KLRF1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KLRF1 Infographic by Boster Bio

All KLRF1 Products

Product

Figures

Specificity

Applications

Price

Anti-KLRF1 Antibody

Human

ELISA, WB

$380
Cat # A09753
100ul

KLRF1 (NM_016523) Human Over-expression Lysate

Human

$628
Cat # LS051348
100 µg

KLRF1 Overview

Facts about Killer cell lectin-like receptor subfamily F member 1.

KLRF1 3D structure. Source: alphafold

Killer cell lectin-like receptor subfamily F member 1 (KLRF1)

Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts. .

Gene Information

Human
Gene Name:	KLRF1
Uniprot:	Q9NZS2
Entrez:	51348

Family

Belongs to:

No superfamily

Alternative Names

Activating coreceptor NKp80; CLEC5C; CLEC5CMGC119908; C-type lectin domain family 5 member C; killer cell lectin-like receptor F1; killer cell lectin-like receptor subfamily F member 1; killer cell lectin-like receptor subfamily F, member 1; KLRF1; Lectin-like receptor F1; MGC119907; MGC119909; ML; NKp80

Molecular Weight

Mass (kDA):
26.563 kDA

Genomic Context


Human

Location:	12p13.31
Sequence:	12; NC_000012.12 (9800052..9845005)

Tissue Specificity

Strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Not expressed in brain, heart, placenta, lung, kidney, skeletal muscle, and pancreas. Within peripheral blood leukocyte and immunocyte cell lines, expression was predominant in NK cells but was also detected in monocytes.

Subcellular Localizations

Membrane; Single-pass type II membrane protein.

Diseases

Neoplasms
Infective Disorder
Malignant Neoplasms
Malignant Paraganglionic Neoplasm
Hiv Infections
Leukemia
Inflammation
Lymphoproliferative Disorders
Simian Acquired Immunodeficiency Syndrome
Leukemia, T-cell
Uterine Cervical Neoplasm
Neoplasms, Experimental
Malignant Neoplasm Of Liver

T-cell Large Granular Lymphocyte Leukemia
Malignant Tumor Of Cervix
Leukemia, Myelocytic, Acute
Immunologic Deficiency Syndromes
Necatoriasis
Myeloid Leukemia
Cervical Intraepithelial Neoplasia

Pathways

Cytolysis
Cell Activation
Chemotaxis
Cell Chemotaxis
Secretion

PTMs

Phosphorylation

Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KLRF1

References

PMID: 10671213 by Roda-Navarro P., et al. Human KLRF1, a novel member of the killer cell lectin-like receptor gene family: molecular characterization, genomic structure, physical mapping to the NK gene complex and expression analysis.

PMID: 11513955 by Roda-Navarro P., et al. Molecular characterization of two novel alternative spliced variants of the KLRF1 gene and subcellular distribution of KLRF1 isoforms.