Kelch-like protein 2 Antibodies

AND KLHL2 ELISA kits, Kelch-like protein 2 Proteins

Many biological assays use antibodies to detect Kelch-like protein 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Kelch-like protein 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Kelch-like protein 2 antibodies...

We validate the specificity of these antibodies to Kelch-like protein 2 by testing them on tissues known to express KLHL2 positively and negatively. Browse below to find the KLHL2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KLHL2 Infographic by Boster Bio

All KLHL2 Products

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Product

Figures

Specificity

Applications

Price

Anti-KLHL2 Mouse Monoclonal Antibody [Clone ID: OTI1G7]

Dog, Human, Monkey, Mouse, Rat

Flow Cytometry, IF, WB

$523
Cat # M09066
100 µl

KLHL2 (NM_007246) Human Over-expression Lysate

Human

$628
Cat # LS011275
100 µg

KLHL2 Overview

Facts about Kelch-like protein 2.

KLHL2 3D structure. Source: alphafold

Kelch-like protein 2 (KLHL2)

Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation (By similarity). Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4.

Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors.

Gene Information

Human
Gene Name:	KLHL2
Uniprot:	O95198
Entrez:	11275

Family

Belongs to:

No superfamily

Alternative Names

ABP-KELCH; Actin-binding protein Mayven; kelch (Drosophila)-like 2 (Mayven); kelch; kelch-like 2, Mayven (Drosophila); kelch-like protein 2; MAV; MAYVEN

Molecular Weight

Mass (kDA):
65.975 kDA

Genomic Context


Human

Location:	4q32.3
Sequence:	4; NC_000004.12 (165207561..165323156)

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell projection, ruffle. Cell projection. Cell projection, lamellipodium. Cytoplasm, cytosol. A proportion colocalizes with the actin cytoskeleton. When over-expressed, colocalizes with NPTXR in perinuclear aggresomes (By similarity).