KIR2DL3 Antibodies

AND KIR2DL3 ELISA kits, KIR2DL3 Proteins

Many biological assays use antibodies to detect KIR2DL3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KIR2DL3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KIR2DL3 antibodies...

We validate the specificity of these antibodies to KIR2DL3 by testing them on tissues known to express KIR2DL3 positively and negatively. Browse below to find the KIR2DL3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KIR2DL3 Infographic by Boster Bio

All KIR2DL3 Products

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Specificity

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Price

Anti-KIR2DL3 Antibody

Human, Mouse

IF, ICC, WB

$405
Cat # A02470
100ul

Human KIR2DL3/CD158b2 Recombinant Protein

SDS-PAGE

$265
Cat # PROTP43628
Starting from 20ug

KIR2DL3 Overview

Facts about Killer cell immunoglobulin-like receptor 2DL3.

KIR2DL3 3D structure. Source: alphafold

Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3)

Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.

Gene Information

Human
Gene Name:	KIR2DL3
Uniprot:	P43628
Entrez:	3804

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

CD158 antigen-like family member B2; CD158b2 antigen; CD158b2; CD158B2CD158b; cl-6; killer cell immunoglobulin-like receptor 2DL3; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3; Killer inhibitory receptor cl 2-3; KIR-023GB; KIR2DL3; KIRCL23; KIR-K7b; KIR-K7c; MGC129943; MHC class I NK cell receptor; natural killer associated transcript 2; natural killer cell inhibitory receptor KIR2DL3; Natural killer-associated transcript 2; NKAT; NKAT2; NKAT-2; NKAT2A; nkat2b; NKAT2GL183; NK-receptor; p58 natural killer cell receptor clone CL-6; p58 NK receptor CL-6; p58; p5

Molecular Weight

Mass (kDA):
37.886 kDA

Genomic Context


Human

Location:	19q13.42
Sequence:	19; NC_000019.10 (54738513..54753052)

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Neoplasms
Hepatitis
Hepatitis C
Hiv Infections
Virus Diseases
Infective Disorder
Leukemia
Dysequilibrium Syndrome
Hepatitis C, Chronic
Carcinoma
Malignant Neoplasms
Hepatitis, Chronic

Graft-vs-host Disease
Autoimmune Reaction
Hematologic Neoplasms
Myeloid Leukemia
Liver Neoplasms
Immunologic Deficiency Syndromes
Rheumatoid Arthritis

Interacting Proteins

HLA-B
HLA-B
HLA-C
HLA-C
HLA-C

HLA-C
HLA-C
HLA-C
PTPN11
PTPN6

Pathways

Cell Activation
Immune Response
Pathogenesis
Cytolysis
Demethylation
Methylation
Cytokine Production
Viral Replication
Secretion
Dna Demethylation
Cytokine Secretion
Innate Immune Response
Cell Proliferation

Dna Methylation
Cell Recognition
Developmental Process
Fibroblast Proliferation
Cell Maturation
Response To Tumor Cell
Cell Division

PTMs

Demethylation
Phosphorylation
Methylation

Deglycosylation
Biotinylation
Citrullination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KIR2DL3

References

PMID: 7716543 by Colonna M., et al. Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells.

PMID: 7749980 by Wagtmann N., et al. Molecular clones of the p58 NK cell receptor reveal immunoglobulin- related molecules with diversity in both the extra- and intracellular domains.