KIF5C Antibodies

AND KIF5C ELISA kits, KIF5C Proteins

Many biological assays use antibodies to detect KIF5C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KIF5C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KIF5C antibodies...

We validate the specificity of these antibodies to KIF5C by testing them on tissues known to express KIF5C positively and negatively. Browse below to find the KIF5C antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KIF5C Infographic by Boster Bio

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Kinesin 5C (KIF5C) (NM_004522) Human Over-expression Lysate

Human

$960
Cat # LS003800
100 µg

KIF5C Overview

Facts about Kinesin heavy chain isoform 5C.

KIF5C 3D structure. Source: alphafold

Kinesin heavy chain isoform 5C (KIF5C)

Involved in synaptic transmission (PubMed:24812067). Mediates dendritic trafficking of mRNAs (By similarity).

Kinesin is a microtubule-associated force-producing protein which may play a role in organelle transport. Required for anterograde axonal transport of MAPK8IP3/JIP3 that's essential for MAPK8IP3/JIP3 function in axon elongation (By similarity).

Gene Information

Human
Gene Name:	KIF5C
Uniprot:	O60282
Entrez:	3800

Family

Belongs to:

TRAFAC class myosin-kinesin ATPase superfamily

Alternative Names

heavy chain, neuron-specific; KIF 5C; kinesin family member 5C; Kinesin heavy chain neuron-specific 2; MGC111478; NKHC; NKHC2NKHC-2

Molecular Weight

Mass (kDA):
109.495 kDA

Genomic Context


Human

Location:	2q23.1-q23.2
Sequence:	2; NC_000002.12 (148875227..149026759)

Tissue Specificity

Highest expression in brain, prostate and testis, and moderate expression in kidney, small intestine and ovary.

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell projection, dendrite. Abundant in distal regions of dendrites.

Diseases

Nervousness
Abnormal Degeneration
Neuroblastoma
Impacted Tooth
Leiomyosarcoma
Developmental Delay (disorder)
Tissue Adhesions
Muscle Hypotonia
Developmental Disabilities
Epilepsy
Virus Diseases

Adenovirus Infections
Fibroid Tumor
Traditional Serrated Adenoma
Uterine Fibroids
Lymphoproliferative Disorder Of The Skin

Interacting Proteins

CSNK2A1
CSNK2A2
RHOT1

Pathways

Transport
Localization
Pathogenesis
Cell Adhesion
Brain Development
Cellular Process
Synaptic Transmission
Intracellular Signal Transduction
Mrna Transport
Energy Homeostasis
Nuclear Export
Spermatogenesis

Cell Division
Translation
Cell Motility
Regulation Of Translation
Nucleocytoplasmic Transport
Meiosis
Secretion

PTMs

Phosphorylation

Acetylation

Research Areas

Cell Biology
Cellular Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KIF5C

References

PMID: 9361024 by Engelender S., et al. Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin.

PMID: 15644324 by Brickley K., et al. GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin.