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KIF2A Antibodies
AND KIF2A ELISA kits, KIF2A Proteins
Many biological assays use antibodies to detect KIF2A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KIF2A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KIF2A antibodies...
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KIF2A Infographic by Boster Bio
All KIF2A Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03979-1
100 μg/vial
Cat # A03979-1
100 μg/vial
Human
$960
Cat # LS003796
100 µg
Cat # LS003796
100 µg
KIF2A Overview
Facts about Kinesin-like protein KIF2A.
Kinesin-like protein KIF2A (KIF2A)
Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth.
Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate.
Gene Information
| Human | |
|---|---|
| Gene Name: | KIF2A |
| Uniprot: | O00139 |
| Entrez: | 3796 |
Family
| Belongs to: |
|---|
| TRAFAC class myosin-kinesin ATPase superfamily |
Alternative Names
HK2; KIF2kinesin-2; kinesin heavy chain member 2; kinesin heavy chain member 2A; Kinesin, heavy chain, 2; Kinesin-2; kinesin-like protein KIF2A; KNS2
Molecular Weight
Mass (kDA):
79.955 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q12.1 |
| Sequence: | 5; NC_000005.10 (62306162..62391025) |
Subcellular Localizations
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1.
Diseases
- Malignant Neoplasms
- Neoplasms
- Tissue Adhesions
- Neoplasm Metastasis
- Tumor Progression
- Cell Invasion
- Abnormal Behavior
- Adenoma
- Tongue Neoplasms
- Malignant Neoplasm Of Tongue
- Metastatic Malignant Neoplasm To The Lymph Node
- Neoplasm Invasiveness
- Malignant Neoplasm Of Lung
Interacting Proteins
- FAM13C
- LARP1B
- MRPL53
Pathways
- Mitosis
- Transport
- Anaphase
- Spindle Assembly
- Metaphase
- Localization
- Cell Cycle
- Chromosome Segregation
- Microtubule Depolymerization
- Rna Interference
- Cytokinesis
- Cell Division
- Synaptic Transmission
PTMs
- Phosphorylation
- Cleavage
Research Areas
- Cancer
- Cell Biology
- Cell Cycle and Replication
- Cellular Markers
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KIF2A
bosterbio.com/bosterbio-gene-info-cards/KIF2A
References
PMID: 9177777 by Debernardi S., et al. Identification of a novel human kinesin-related gene (HK2) by the cDNA differential display technique.
PMID: 15843429 by Zhu C., et al. Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference.