KIF23 Antibodies

AND KIF23 ELISA kits, KIF23 Proteins

Many biological assays use antibodies to detect KIF23, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KIF23 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KIF23 antibodies...

We validate the specificity of these antibodies to KIF23 by testing them on tissues known to express KIF23 positively and negatively. Browse below to find the KIF23 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KIF23 Infographic by Boster Bio

All KIF23 Products

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Specificity

Applications

Price

Anti-MKLP1 KIF23 Rabbit Monoclonal Antibody

5 Q&As

Human, Mouse, Rat

IF, ICC, WB

$370
Cat # M03483
100 μl

Anti-Kinesin-like protein KIF23 KIF23 Antibody

Human

ELISA, WB

$380
Cat # A03483
100ul

KIF23 Overview

Facts about Kinesin-like protein KIF23.

KIF23 3D structure. Source: alphafold

Kinesin-like protein KIF23 (KIF23)

Part of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling.

Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro.

Gene Information

Human
Gene Name:	KIF23
Uniprot:	Q02241
Entrez:	9493

Family

Belongs to:

TRAFAC class myosin-kinesin ATPase superfamily

Alternative Names

kinesin family member 23; kinesin-like 5 (mitotic kinesin-like protein 1); Kinesin-like protein 5; kinesin-like protein KIF23; KNSL5CHO1; mitotic kinesin-like 1; MKLP-1; MKLP1Mitotic kinesin-like protein 1

Molecular Weight

Mass (kDA):
110.059 kDA

Genomic Context


Human

Location:	15q23
Sequence:	15; NC_000015.10 (69414325..69448427)

Subcellular Localizations

Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody, Midbody ring. Localizes to the interzone of mitotic spindles. Detected at the midbody during later stages of mitotic cytokinesis.

Diseases

Malignant Neoplasms
Neoplasms
Nervousness
Adenocarcinoma
Colonic Neoplasms
Malignant Tumor Of Colon
Glioma
Bone Neoplasms
Aneuploidy
Neoplasm Invasiveness
Malignant Neoplasm Of Lung
Carcinoma
Osteosarcoma

Fibrosarcoma
Lymphoma
Chimera Disorder
Riboflavin Deficiency
Cell Invasion
Malignant Neoplasm Of Prostate
Malignant Squamous Cell Neoplasm

Interacting Proteins

ARF6
Arf6
BIRC6
ECT2
RACGAP1

YWHAG
YWHAZ

Pathways

Cytokinesis
Localization
Anaphase
Cell Division
Mitosis
Cell Cycle
Chromosome Segregation
Metaphase
Abscission
Transport
Cell Proliferation
Cell Cycle Arrest
Interphase

Telophase
Spindle Localization
M Phase
Spindle Assembly
Rna Interference
Cleavage Furrow Formation
Cell Migration

PTMs

Phosphorylation
Cleavage

Glycosylation
Acetylation

Dephosphorylation

Research Areas

Cell Cycle and Replication
Core ESC-Like Genes
DNA Repair
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KIF23

References

PMID: 1406973 by Nislow C., et al. A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles.

PMID: 11782313 by Mishima M., et al. Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity.