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- Table of Contents
Facts about Keratocan.
Human | |
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Gene Name: | KERA |
Uniprot: | O60938 |
Entrez: | 11081 |
Belongs to: |
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small leucine-rich proteoglycan (SLRP) family |
CNA2; KERA; Keratocan; KTN; SLRR2B; SLRR2BKeratan sulfate proteoglycan keratocan
Mass (kDA):
40.509 kDA
Human | |
---|---|
Location: | 12q21.33 |
Sequence: | 12; NC_000012.12 (91050491..91058024, complement) |
Cornea (at protein level) (PubMed:10802664, PubMed:11683372). Increased expression in the stroma of keratoconus corneas (PubMed:11683372). Also detected in trachea, and in low levels, in intestine, skeletal muscle, ovary, lung and putamen (PubMed:10802664).
Secreted, extracellular space, extracellular matrix.
PMID: 10565548 by Tasheva E.S., et al. Structure and sequence of the gene encoding human keratocan.
PMID: 10802664 by Pellegata N.S., et al. Mutations in KERA, encoding keratocan, cause cornea plana.