Keratocan Antibodies

Keratocan (KERA)

May be important in creating and maintaining corneal transparency and for the structure of the stromal matrix. .

Gene Information

Human
Gene Name:	KERA
Uniprot:	O60938
Entrez:	11081

Family

Belongs to:
small leucine-rich proteoglycan (SLRP) family

Alternative Names

CNA2; KERA; Keratocan; KTN; SLRR2B; SLRR2BKeratan sulfate proteoglycan keratocan

Molecular Weight

Mass (kDA):
40.509 kDA

Genomic Context

Human
Location:	12q21.33
Sequence:	12; NC_000012.12 (91050491..91058024, complement)

Tissue Specificity

Cornea (at protein level) (PubMed:10802664, PubMed:11683372). Increased expression in the stroma of keratoconus corneas (PubMed:11683372). Also detected in trachea, and in low levels, in intestine, skeletal muscle, ovary, lung and putamen (PubMed:10802664).

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

• Corneal Diseases
• Cornea Plana
• Hereditary Corneal Dystrophy
• Myopia
• Cicatrix
• Visual Impairment
• Scleral Diseases
• Congenital Abnormality
• Glaucoma
• Dystrophy
• Inflammation

• Edema
• Tissue Adhesions
• Corneal Ectasia
• Corneal Edema
• Cytomegalovirus Infections
• Hereditary Diseases

Pathways

• Wound Healing
• Cell Proliferation
• Inflammatory Response
• Reverse Transcription
• Eye Development
• Localization
• Senescence
• Coagulation
• Transport
• Fibril Organization
• Cell Migration
• Osteoblast Differentiation
• Immune Response

• Proteolysis
• Limb Development
• Eye Morphogenesis
• Replicative Senescence
• Phagocytosis
• Cell Differentiation
• Collagen Fibril Organization

PTMs

• Phosphorylation

• Hydroxylation

• Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KERA

Boster Bio - Best Uses Of The KERA Marker

Boster Bio sells high-affinity primary antibody kits. Their antibodies are well-validated on Western Blotting, Immunohistochemistry, and ELISA methods, making them an excellent choice for your research. In addition to these antibodies, Boster also offers a KERA Marker, which can be used in the study of a variety of cellular processes.

Boster offers high-affinity prim antibodies

To facilitate cancer immunotherapy, Boster Bio provides high-affinity primary antibodies against the Kera marker. This product targets the cellular membrane bound carcinoembryonic antibody and is highly specific to its target. The monovalent heterodimeric IgGs are available as monovalent, bispecific heterodimeric IgGs. These monovalent biochemical antibodies are highly compatible and can be used to enhance the cytotoxicity or phagocytotoxicity.