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- Table of Contents
Facts about Lysine-specific demethylase 5D.
May play a role in spermatogenesis. Involved in transcriptional repression of varied metastasis-associated genes; in this function seems to cooperate with ZMYND8.
Human | |
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Gene Name: | KDM5D |
Uniprot: | Q9BY66 |
Entrez: | 8284 |
Belongs to: |
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JARID1 histone demethylase family |
Lysine-specific demethylase 5D
Mass (kDA):
174.073 kDA
Human | |
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Location: | Yq11.223 |
Sequence: | Y; NC_000024.10 (19703865..19745341, complement) |
Expression is highly down-regulated in metastatic prostate tumors.
Nucleus.
PMID: 8841177 by Kent-First M.G., et al. Gene sequence and evolutionary conservation of human SMCY.
PMID: 10861003 by Shen P., et al. Population genetic implications from sequence variation in four Y chromosome genes.